Lifestyle and 25-hydroxy-vitamin D among community-dwelling old adults with dementia, mild cognitive impairment, or normal cognitive function
Background Several studies have indicated that older adults with cognitive impairment have a poorer lifestyle than their healthy peers including lower 25-hydroxy-vitamin D levels (25OHD). Aim To investigate the associations between lifestyle and 25OHD depending on cognitive status among old adults....
Gespeichert in:
| Veröffentlicht in: | Aging clinical and experimental research 2020-12, Vol.32 (12), p.2649-2656 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2656 |
|---|---|
| container_issue | 12 |
| container_start_page | 2649 |
| container_title | Aging clinical and experimental research |
| container_volume | 32 |
| creator | Eymundsdottir, Hrafnhildur Chang, M. Geirsdottir, O. G. Gudmundsson, L. S. Jonsson, P. V. Gudnason, V. Launer, L. Jonsdottir, M. K. Ramel, A. |
| description | Background
Several studies have indicated that older adults with cognitive impairment have a poorer lifestyle than their healthy peers including lower 25-hydroxy-vitamin D levels (25OHD).
Aim
To investigate the associations between lifestyle and 25OHD depending on cognitive status among old adults.
Methods
Community-dwelling old adults (65–96 years) participated in this cross-sectional study based on the Age-Gene/Environment-Susceptibility-Reykjavik-Study. The analytical sample included 5162 subjects who were stratified by cognitive status, i.e., dementia (
n
= 307), mild cognitive impairment (MCI,
n
= 492), and normal cognitive status (NCS,
n
= 4363). Lifestyle variables were assessed and 25OHD was measured. The associations between lifestyle and 25OHD were calculated using linear models correcting for potential confounders.
Results
According to linear regression models, 25OHD was significantly lower in older people with dementia (53.8 ± 19.6 nmol/L) than in NCS participants (57.6 ± 17.7 nmol/L). Cod liver oil (7.1–9.2 nmol/L,
P
|
| doi_str_mv | 10.1007/s40520-020-01531-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9233863</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2386430274</sourcerecordid><originalsourceid>FETCH-LOGICAL-c474t-b336610a1bf3f690a7489a7834dd770cd6c59147953e471ea46297d21f52e0f43</originalsourceid><addsrcrecordid>eNp9UctO3DAUtRAVr_YHWCBLbFgQ8CtxskFCUFqkkdi0a8tjOzNGsT3YyUA-gn-uo6EwZdGFZV-fc899HACOMbrACPHLxFBJUIGmg0uKC7wDDjDPYU1xs7v13geHKT0ixHAO9sA-JYTVtKwPwOvMtib1Y2eg9BqSsliOOoaXsVjbXjrr4S2ULvgFVMG5wdt-LPSz6Tqbv0KnodRD1yf4bPsl1MYZ31t5Dp3NkAqLzLdrA61bSRsn8ByGCH2ITnZbeDt41dvgv4IvreyS-fZ2H4Hfd99_3fwsZg8_7m-uZ4VinPXFnNKqwkjieUvbqkGSs7qRvKZMa86R0pUqG8x4U1LDODaSVaThmuC2JAa1jB6Bq43uapg7o1VuLMpOrKJ1Mo4iSCv-RbxdikVYi4ZQWlc0C5y9CcTwNOQFCmeTymuR3oQhCZJZjCLCp1qnn6iPYYg-jycI43mSuiY8s8iGpWJIKZr2vRmMxOS22Lgt0HQmtwXOSSfbY7yn_LU3E-iGkDLkFyZ-1P6P7B9ia7d6</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2473368827</pqid></control><display><type>article</type><title>Lifestyle and 25-hydroxy-vitamin D among community-dwelling old adults with dementia, mild cognitive impairment, or normal cognitive function</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Eymundsdottir, Hrafnhildur ; Chang, M. ; Geirsdottir, O. G. ; Gudmundsson, L. S. ; Jonsson, P. V. ; Gudnason, V. ; Launer, L. ; Jonsdottir, M. K. ; Ramel, A.</creator><creatorcontrib>Eymundsdottir, Hrafnhildur ; Chang, M. ; Geirsdottir, O. G. ; Gudmundsson, L. S. ; Jonsson, P. V. ; Gudnason, V. ; Launer, L. ; Jonsdottir, M. K. ; Ramel, A.</creatorcontrib><description><![CDATA[Background
Several studies have indicated that older adults with cognitive impairment have a poorer lifestyle than their healthy peers including lower 25-hydroxy-vitamin D levels (25OHD).
Aim
To investigate the associations between lifestyle and 25OHD depending on cognitive status among old adults.
Methods
Community-dwelling old adults (65–96 years) participated in this cross-sectional study based on the Age-Gene/Environment-Susceptibility-Reykjavik-Study. The analytical sample included 5162 subjects who were stratified by cognitive status, i.e., dementia (
n
= 307), mild cognitive impairment (MCI,
n
= 492), and normal cognitive status (NCS,
n
= 4363). Lifestyle variables were assessed and 25OHD was measured. The associations between lifestyle and 25OHD were calculated using linear models correcting for potential confounders.
Results
According to linear regression models, 25OHD was significantly lower in older people with dementia (53.8 ± 19.6 nmol/L) than in NCS participants (57.6 ± 17.7 nmol/L). Cod liver oil (7.1–9.2 nmol/L,
P
< 0.001) and dietary supplements (4.4–11.5 nmol/L,
P
< 0.001) were associated with higher 25OHD in all three groups. However, physical activity ≥ 3 h/week (2.82 nmol/L,
P
< 0.001), BMI < 30 kg/m
2
(5.2 nmol/L,
P
< 0.001), non-smoking (4.8 nmol/L,
P
< 0.001), alcohol consumption (2.7 nmol/L,
P
< 0.001), and fatty fish consumption ≥ 3
x
/week (2.6 nmol/L,
P
< 0.001) were related to higher 25OHD in NCS only, but not in participants with dementia or MCI.
Discussion
Older people living in Iceland with dementia are at higher risk for 25OHD deficiency when compared to healthy individuals. Physical activity reported among participants with dementia, and MCI is low and is not significantly associated with 25OHD.
Conclusions
Lifestyle factors among NCS participants are associated with 25OHD levels. Importantly, healthy lifestyle should be promoted among individuals with MCI and dementia.]]></description><identifier>ISSN: 1720-8319</identifier><identifier>ISSN: 1594-0667</identifier><identifier>EISSN: 1720-8319</identifier><identifier>DOI: 10.1007/s40520-020-01531-1</identifier><identifier>PMID: 32248358</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Aged ; Aged, 80 and over ; Cognition ; Cognitive ability ; Cognitive Dysfunction ; Cross-Sectional Studies ; Dementia ; Exercise ; Geriatrics/Gerontology ; Humans ; Independent Living ; Life Style ; Lifestyles ; Medicine ; Medicine & Public Health ; Older people ; Original Article ; Vitamin D ; Vitamin D Deficiency</subject><ispartof>Aging clinical and experimental research, 2020-12, Vol.32 (12), p.2649-2656</ispartof><rights>Springer Nature Switzerland AG 2020</rights><rights>Springer Nature Switzerland AG 2020.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-b336610a1bf3f690a7489a7834dd770cd6c59147953e471ea46297d21f52e0f43</citedby><cites>FETCH-LOGICAL-c474t-b336610a1bf3f690a7489a7834dd770cd6c59147953e471ea46297d21f52e0f43</cites><orcidid>0000-0002-5614-0315</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s40520-020-01531-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s40520-020-01531-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32248358$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eymundsdottir, Hrafnhildur</creatorcontrib><creatorcontrib>Chang, M.</creatorcontrib><creatorcontrib>Geirsdottir, O. G.</creatorcontrib><creatorcontrib>Gudmundsson, L. S.</creatorcontrib><creatorcontrib>Jonsson, P. V.</creatorcontrib><creatorcontrib>Gudnason, V.</creatorcontrib><creatorcontrib>Launer, L.</creatorcontrib><creatorcontrib>Jonsdottir, M. K.</creatorcontrib><creatorcontrib>Ramel, A.</creatorcontrib><title>Lifestyle and 25-hydroxy-vitamin D among community-dwelling old adults with dementia, mild cognitive impairment, or normal cognitive function</title><title>Aging clinical and experimental research</title><addtitle>Aging Clin Exp Res</addtitle><addtitle>Aging Clin Exp Res</addtitle><description><![CDATA[Background
Several studies have indicated that older adults with cognitive impairment have a poorer lifestyle than their healthy peers including lower 25-hydroxy-vitamin D levels (25OHD).
Aim
To investigate the associations between lifestyle and 25OHD depending on cognitive status among old adults.
Methods
Community-dwelling old adults (65–96 years) participated in this cross-sectional study based on the Age-Gene/Environment-Susceptibility-Reykjavik-Study. The analytical sample included 5162 subjects who were stratified by cognitive status, i.e., dementia (
n
= 307), mild cognitive impairment (MCI,
n
= 492), and normal cognitive status (NCS,
n
= 4363). Lifestyle variables were assessed and 25OHD was measured. The associations between lifestyle and 25OHD were calculated using linear models correcting for potential confounders.
Results
According to linear regression models, 25OHD was significantly lower in older people with dementia (53.8 ± 19.6 nmol/L) than in NCS participants (57.6 ± 17.7 nmol/L). Cod liver oil (7.1–9.2 nmol/L,
P
< 0.001) and dietary supplements (4.4–11.5 nmol/L,
P
< 0.001) were associated with higher 25OHD in all three groups. However, physical activity ≥ 3 h/week (2.82 nmol/L,
P
< 0.001), BMI < 30 kg/m
2
(5.2 nmol/L,
P
< 0.001), non-smoking (4.8 nmol/L,
P
< 0.001), alcohol consumption (2.7 nmol/L,
P
< 0.001), and fatty fish consumption ≥ 3
x
/week (2.6 nmol/L,
P
< 0.001) were related to higher 25OHD in NCS only, but not in participants with dementia or MCI.
Discussion
Older people living in Iceland with dementia are at higher risk for 25OHD deficiency when compared to healthy individuals. Physical activity reported among participants with dementia, and MCI is low and is not significantly associated with 25OHD.
Conclusions
Lifestyle factors among NCS participants are associated with 25OHD levels. Importantly, healthy lifestyle should be promoted among individuals with MCI and dementia.]]></description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cognition</subject><subject>Cognitive ability</subject><subject>Cognitive Dysfunction</subject><subject>Cross-Sectional Studies</subject><subject>Dementia</subject><subject>Exercise</subject><subject>Geriatrics/Gerontology</subject><subject>Humans</subject><subject>Independent Living</subject><subject>Life Style</subject><subject>Lifestyles</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Older people</subject><subject>Original Article</subject><subject>Vitamin D</subject><subject>Vitamin D Deficiency</subject><issn>1720-8319</issn><issn>1594-0667</issn><issn>1720-8319</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9UctO3DAUtRAVr_YHWCBLbFgQ8CtxskFCUFqkkdi0a8tjOzNGsT3YyUA-gn-uo6EwZdGFZV-fc899HACOMbrACPHLxFBJUIGmg0uKC7wDDjDPYU1xs7v13geHKT0ixHAO9sA-JYTVtKwPwOvMtib1Y2eg9BqSsliOOoaXsVjbXjrr4S2ULvgFVMG5wdt-LPSz6Tqbv0KnodRD1yf4bPsl1MYZ31t5Dp3NkAqLzLdrA61bSRsn8ByGCH2ITnZbeDt41dvgv4IvreyS-fZ2H4Hfd99_3fwsZg8_7m-uZ4VinPXFnNKqwkjieUvbqkGSs7qRvKZMa86R0pUqG8x4U1LDODaSVaThmuC2JAa1jB6Bq43uapg7o1VuLMpOrKJ1Mo4iSCv-RbxdikVYi4ZQWlc0C5y9CcTwNOQFCmeTymuR3oQhCZJZjCLCp1qnn6iPYYg-jycI43mSuiY8s8iGpWJIKZr2vRmMxOS22Lgt0HQmtwXOSSfbY7yn_LU3E-iGkDLkFyZ-1P6P7B9ia7d6</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>Eymundsdottir, Hrafnhildur</creator><creator>Chang, M.</creator><creator>Geirsdottir, O. G.</creator><creator>Gudmundsson, L. S.</creator><creator>Jonsson, P. V.</creator><creator>Gudnason, V.</creator><creator>Launer, L.</creator><creator>Jonsdottir, M. K.</creator><creator>Ramel, A.</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-5614-0315</orcidid></search><sort><creationdate>20201201</creationdate><title>Lifestyle and 25-hydroxy-vitamin D among community-dwelling old adults with dementia, mild cognitive impairment, or normal cognitive function</title><author>Eymundsdottir, Hrafnhildur ; Chang, M. ; Geirsdottir, O. G. ; Gudmundsson, L. S. ; Jonsson, P. V. ; Gudnason, V. ; Launer, L. ; Jonsdottir, M. K. ; Ramel, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-b336610a1bf3f690a7489a7834dd770cd6c59147953e471ea46297d21f52e0f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cognition</topic><topic>Cognitive ability</topic><topic>Cognitive Dysfunction</topic><topic>Cross-Sectional Studies</topic><topic>Dementia</topic><topic>Exercise</topic><topic>Geriatrics/Gerontology</topic><topic>Humans</topic><topic>Independent Living</topic><topic>Life Style</topic><topic>Lifestyles</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Older people</topic><topic>Original Article</topic><topic>Vitamin D</topic><topic>Vitamin D Deficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eymundsdottir, Hrafnhildur</creatorcontrib><creatorcontrib>Chang, M.</creatorcontrib><creatorcontrib>Geirsdottir, O. G.</creatorcontrib><creatorcontrib>Gudmundsson, L. S.</creatorcontrib><creatorcontrib>Jonsson, P. V.</creatorcontrib><creatorcontrib>Gudnason, V.</creatorcontrib><creatorcontrib>Launer, L.</creatorcontrib><creatorcontrib>Jonsdottir, M. K.</creatorcontrib><creatorcontrib>Ramel, A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Aging clinical and experimental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eymundsdottir, Hrafnhildur</au><au>Chang, M.</au><au>Geirsdottir, O. G.</au><au>Gudmundsson, L. S.</au><au>Jonsson, P. V.</au><au>Gudnason, V.</au><au>Launer, L.</au><au>Jonsdottir, M. K.</au><au>Ramel, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lifestyle and 25-hydroxy-vitamin D among community-dwelling old adults with dementia, mild cognitive impairment, or normal cognitive function</atitle><jtitle>Aging clinical and experimental research</jtitle><stitle>Aging Clin Exp Res</stitle><addtitle>Aging Clin Exp Res</addtitle><date>2020-12-01</date><risdate>2020</risdate><volume>32</volume><issue>12</issue><spage>2649</spage><epage>2656</epage><pages>2649-2656</pages><issn>1720-8319</issn><issn>1594-0667</issn><eissn>1720-8319</eissn><abstract><![CDATA[Background
Several studies have indicated that older adults with cognitive impairment have a poorer lifestyle than their healthy peers including lower 25-hydroxy-vitamin D levels (25OHD).
Aim
To investigate the associations between lifestyle and 25OHD depending on cognitive status among old adults.
Methods
Community-dwelling old adults (65–96 years) participated in this cross-sectional study based on the Age-Gene/Environment-Susceptibility-Reykjavik-Study. The analytical sample included 5162 subjects who were stratified by cognitive status, i.e., dementia (
n
= 307), mild cognitive impairment (MCI,
n
= 492), and normal cognitive status (NCS,
n
= 4363). Lifestyle variables were assessed and 25OHD was measured. The associations between lifestyle and 25OHD were calculated using linear models correcting for potential confounders.
Results
According to linear regression models, 25OHD was significantly lower in older people with dementia (53.8 ± 19.6 nmol/L) than in NCS participants (57.6 ± 17.7 nmol/L). Cod liver oil (7.1–9.2 nmol/L,
P
< 0.001) and dietary supplements (4.4–11.5 nmol/L,
P
< 0.001) were associated with higher 25OHD in all three groups. However, physical activity ≥ 3 h/week (2.82 nmol/L,
P
< 0.001), BMI < 30 kg/m
2
(5.2 nmol/L,
P
< 0.001), non-smoking (4.8 nmol/L,
P
< 0.001), alcohol consumption (2.7 nmol/L,
P
< 0.001), and fatty fish consumption ≥ 3
x
/week (2.6 nmol/L,
P
< 0.001) were related to higher 25OHD in NCS only, but not in participants with dementia or MCI.
Discussion
Older people living in Iceland with dementia are at higher risk for 25OHD deficiency when compared to healthy individuals. Physical activity reported among participants with dementia, and MCI is low and is not significantly associated with 25OHD.
Conclusions
Lifestyle factors among NCS participants are associated with 25OHD levels. Importantly, healthy lifestyle should be promoted among individuals with MCI and dementia.]]></abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>32248358</pmid><doi>10.1007/s40520-020-01531-1</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-5614-0315</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1720-8319 |
| ispartof | Aging clinical and experimental research, 2020-12, Vol.32 (12), p.2649-2656 |
| issn | 1720-8319 1594-0667 1720-8319 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9233863 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Aged Aged, 80 and over Cognition Cognitive ability Cognitive Dysfunction Cross-Sectional Studies Dementia Exercise Geriatrics/Gerontology Humans Independent Living Life Style Lifestyles Medicine Medicine & Public Health Older people Original Article Vitamin D Vitamin D Deficiency |
| title | Lifestyle and 25-hydroxy-vitamin D among community-dwelling old adults with dementia, mild cognitive impairment, or normal cognitive function |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T19%3A06%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lifestyle%20and%2025-hydroxy-vitamin%20D%20among%20community-dwelling%20old%20adults%20with%20dementia,%20mild%20cognitive%20impairment,%20or%20normal%20cognitive%20function&rft.jtitle=Aging%20clinical%20and%20experimental%20research&rft.au=Eymundsdottir,%20Hrafnhildur&rft.date=2020-12-01&rft.volume=32&rft.issue=12&rft.spage=2649&rft.epage=2656&rft.pages=2649-2656&rft.issn=1720-8319&rft.eissn=1720-8319&rft_id=info:doi/10.1007/s40520-020-01531-1&rft_dat=%3Cproquest_pubme%3E2386430274%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2473368827&rft_id=info:pmid/32248358&rfr_iscdi=true |