The Molecular Basis and Therapeutic Potential of Leukemia Inhibitory Factor in Cancer Cachexia

Cachexia is a chronic metabolic syndrome that is characterized by sustained weight and muscle mass loss and anorexia. Cachexia can be secondary to a variety of diseases and affects the prognosis of patients significantly. The increase in inflammatory cytokines in plasma is deeply related to the occu...

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Veröffentlicht in:	Cancers 2022-06, Vol.14 (12), p.2955
Hauptverfasser:	Zeng, Ruijiang, Tong, Chang, Xiong, Xiangyang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Amino acids Anorexia Atrophy Autocrine signalling Bone cancer Cachexia Cancer Cancer therapies Care and treatment Colorectal cancer Complications and side effects Cytokines Development and progression Disease Eating disorders Esophagus Genes Glycoproteins Health aspects Inflammation Interleukin 6 Leukemia Leukemia inhibitory factor Medical prognosis Metabolic syndrome Metabolism Metastases Mortality Musculoskeletal system Ovaries Pancreatic cancer Paracrine signalling Patients Proteins Review Signal transduction Skeletal muscle Stem cells Stromal cells Testicular cancer Tumor necrosis factor-TNF Tumors
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