Negative interaction between nitrates and remote ischemic preconditioning in patients undergoing cardiac surgery: the ERIC-GTN and ERICCA studies

Remote ischaemic preconditioning (RIPC) using transient limb ischaemia failed to improve clinical outcomes following cardiac surgery and the reasons for this remain unclear. In the ERIC-GTN study, we evaluated whether concomitant nitrate therapy abrogated RIPC cardioprotection. We also undertook a p...

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Veröffentlicht in:	Basic research in cardiology 2022-12, Vol.117 (1), p.31-31, Article 31
Hauptverfasser:	Hamarneh, Ashraf, Ho, Andrew Fu Wah, Bulluck, Heerajnarain, Sivaraman, Vivek, Ricciardi, Federico, Nicholas, Jennifer, Shanahan, Hilary, Hardman, Elizabeth A., Wicks, Peter, Ramlall, Manish, Chung, Robin, McGowan, John, Cordery, Roger, Lawrence, David, Clayton, Tim, Kyle, Bonnie, Xenou, Maria, Ariti, Cono, Yellon, Derek M., Hausenloy, Derek J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood pressure Calcium-binding protein Cardiac Surgical Procedures - adverse effects Cardiology Cardiovascular diseases Clinical outcomes Heart Heart attacks Heart surgery Humans Intravenous administration Intravenous infusion Ischemia Ischemic Preconditioning - adverse effects Ischemic Preconditioning, Myocardial Medicine Medicine & Public Health Mortality Myocardial infarction Myocardial Infarction - etiology Nitrates Original Contribution Patients Preconditioning Risk Surgery Treatment Outcome Troponin Troponin T
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