Left Atrial Appendage Occlusion as an Alternative to Anticoagulants in Ibrutinib-Induced Hemorrhagic Pericardial Effusion

Bleeding tendency increases with concomitant use of ibrutinib and anticoagulants. Our patient presented with shortness of breath and was found to have a nonmalignant hemorrhagic pericardial effusion. Ibrutinib was resumed, and percutaneous left atrial appendage occlusion was performed as a substitut...

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Veröffentlicht in:JACC. Case reports 2022-06, Vol.4 (12), p.751-754
Hauptverfasser: Jeelani, Hafiz, Sheikh, Muhammad Mubbashir, Tahir, Nayha, Ying, Grace, Prasad, Sonika, Yaremko, Maryana, Gill, Jashan
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container_issue 12
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container_title JACC. Case reports
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creator Jeelani, Hafiz
Sheikh, Muhammad Mubbashir
Tahir, Nayha
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Prasad, Sonika
Yaremko, Maryana
Gill, Jashan
description Bleeding tendency increases with concomitant use of ibrutinib and anticoagulants. Our patient presented with shortness of breath and was found to have a nonmalignant hemorrhagic pericardial effusion. Ibrutinib was resumed, and percutaneous left atrial appendage occlusion was performed as a substitute for the chemical anticoagulation to decrease the drug-drug interaction. ( Level of Difficulty: Intermediate. )
doi_str_mv 10.1016/j.jaccas.2022.01.027
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title Left Atrial Appendage Occlusion as an Alternative to Anticoagulants in Ibrutinib-Induced Hemorrhagic Pericardial Effusion
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