Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9

Vaccinia virus (VACV) represents a family of poxviruses, which possess their own decapping machinery as a part of their strategy to eliminate host mRNAs and evade the innate immune response. D9 is one of the two encoded VACV decapping enzymes that is responsible for cap removal from the 5′ end of bo...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ACS chemical biology 2022-06, Vol.17 (6), p.1460-1471
Hauptverfasser:	Bednarczyk, Marcelina, Peters, Jessica K., Kasprzyk, Renata, Starek, Jagoda, Warminski, Marcin, Spiewla, Tomasz, Mugridge, Jeffrey S., Gross, John D., Jemielity, Jacek, Kowalska, Joanna
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!