Decorin antagonizes corneal fibroblast migration via caveolae-mediated endocytosis of epidermal growth factor receptor

Decorin (Dcn), a small leucine-rich proteoglycan, is involved in the regulation of corneal wound healing. Epidermal growth factor receptor (EGFR) plays a critical role in corneal fibroblasts proliferation, migration and extracellular matrix (ECM) modulation upon injury or infection. The present stud...

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Veröffentlicht in:	Experimental eye research 2019-03, Vol.180, p.200-207
Hauptverfasser:	Mohan, Rajiv R., Tripathi, Ratnakar, Sharma, Ajay, Sinha, Prashant R., Giuliano, Elizabeth A., Hesemann, Nathan P., Chaurasia, Shyam S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Caveolae Corneal wound healing Decorin Endocytosis Epidermal growth factor receptor
Online-Zugang:	Volltext
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