Point-of-care COVID-19 testing: colorimetric diagnosis using rapid and ultra-sensitive ramified rolling circle amplification

In this paper, we report a molecular diagnostic system—combining a colorimetric probe ( RHthio-CuSO 4 ) for pyrophosphate sensing and isothermal gene amplification (ramified rolling circle amplification)—that operates with high selectivity and sensitivity for clinical point-of-care diagnosis of SARS...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2022-08, Vol.414 (19), p.5907-5915
Hauptverfasser:	Choi, Moon Hyeok, Kumara, Guralamatta Siddappa Ravi, Lee, Jaehyeon, Seo, Young Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Analysis Analytical Chemistry Biochemistry Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Colorimetry Control Copper sulfate Coronaviruses COVID-19 COVID-19 diagnostic tests Diagnosis Diagnostic systems Epidemics Food Science Gene amplification Genomes Genomics Instrumentation Laboratory Medicine Methods Monitoring/Environmental Analysis Nucleotides Research Paper Respiratory syncytial virus Selectivity Sensitivity Severe acute respiratory syndrome coronavirus 2 South Korea Temperature requirements Viral diseases Viruses
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