A novel flow cytometry procoagulant assay for diagnosis of vaccine-induced immune thrombotic thrombocytopenia

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe prothrombotic complication of adenoviral vaccines, including the ChAdOx1 nCoV-19 (Vaxzevria) vaccine. The putative mechanism involves formation of pathological anti–platelet factor 4 (PF4) antibodies that activate platelets via th...

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Veröffentlicht in:	Blood advances 2022-06, Vol.6 (11), p.3494-3506
Hauptverfasser:	Lee, Christine S.M., Liang, Hai Po Helena, Connor, David E., Dey, Agnibesh, Tohidi-Esfahani, Ibrahim, Campbell, Heather, Whittaker, Shane, Capraro, David, Favaloro, Emmanuel J., Donikian, Dea, Kondo, Mayuko, Hicks, Sarah M., Choi, Philip Y.-I., Gardiner, Elizabeth E., Clarke, Lisa Joanne, Tran, Huyen, Passam, Freda H., Brighton, Timothy Andrew, Chen, Vivien M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Thrombosis and Hemostasis
Online-Zugang:	Volltext
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