The retromer complex regulates C. elegans development and mammalian ciliogenesis

The mammalian retromer consists of subunits VPS26 (either VPS26A or VPS26B), VPS29 and VPS35, and a loosely associated sorting nexin (SNX) heterodimer or a variety of other SNX proteins. Despite involvement in yeast and mammalian cell trafficking, the role of retromer in development is poorly unders...

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Veröffentlicht in:	Journal of cell science 2022-05, Vol.135 (10)
Hauptverfasser:	Xie, Shuwei, Dierlam, Carter, Smith, Ellie, Duran, Ramon, Williams, Allana, Davis, Angelina, Mathew, Danita, Naslavsky, Naava, Iyer, Jyoti, Caplan, Steve
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Cilia and Flagella Endosomes - metabolism Mammals - metabolism Protein Transport Sorting Nexins - genetics Sorting Nexins - metabolism Vesicular Transport Proteins - genetics Vesicular Transport Proteins - metabolism
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