Immunogenicity of candidate SARS-CoV-2 DNA vaccines based on the spike protein

Coronavirus disease 2019 caused by the novel human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently a major threat to public health worldwide. To deal with the needs of vaccine, we developed four DNA vaccine candidates against SARS-CoV-2, based on the full-length spike (S) o...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2022-08, Vol.573, p.118-123
Hauptverfasser:	Lim, Heeji, Kim, Se Eun, Lee, Yun Ha, Hwang, Yun-Ho, Kim, Su Hwan, Kim, Mi Young, Chung, Gyung Tae, Kim, You-Jin, Kim, Dokeun, Lee, Jung-Ah
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Neutralizing Antibodies, Viral antigens Brief Communication COVID-19 - prevention & control COVID-19 infection COVID-19 Vaccines - genetics cytokines DNA DNA vaccine Humans immune response immunogenicity Mice public health recombinant vaccines SARS-CoV-2 SARS-CoV-2 - genetics Severe acute respiratory syndrome coronavirus 2 Spike Glycoprotein, Coronavirus - genetics Spike protein T-lymphocytes Vaccination Vaccines, DNA Viral Vaccines virology
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