Pilot Investigation on p75ICD Expression in Laryngeal Squamous Cell Carcinoma

We investigated the p75 Neurotrophin Receptor (p75NTR) expression and cleavage product p75NTR Intracellular Domain (p75ICD) as potential oncogenic and metastatic markers in human Laryngeal Squamous Cell Carcinoma (LSCC). p75NTR is highly expressed in Cancer Stem Cells (CSCs) of the laryngeal epithel...

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Veröffentlicht in:	Cancers 2022-05, Vol.14 (11), p.2622
Hauptverfasser:	Triaca, Viviana, Fico, Elena, Rosso, Pamela, Ralli, Massimo, Corsi, Alessandro, Severini, Cinzia, Crevenna, Alvaro, Agostinelli, Enzo, Rullo, Emma, Riminucci, Mara, Colizza, Andrea, Polimeni, Antonella, Greco, Antonio, Tirassa, Paola
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Biological markers Cancer therapies Cell cycle Cell migration Chemotherapy Development and progression Diagnosis Genetic aspects Growth factor receptors Head & neck cancer Health aspects Identification and classification Laryngeal cancer Larynx Localization Lymphatic system Medical prognosis Metastases Metastasis Neurotrophic factors Neurotrophic functions Parenchyma Pathology Patients Physiological aspects Solid tumors Squamous cell carcinoma Stem cells Surgery Tumorigenesis Tumors
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