Different types of reactions to E7386 among colorectal cancer patient-derived organoids and corresponding CAFs

Colorectal cancer (CRC) harbors genetic alterations in a component of the Wnt signaling pathway in ~90% of cases. In addition, the Wnt signaling pathway has been previously suggested to serve a notable role in the pathophysiology of CRC cells and cancer-associated fibroblasts (CAFs). In the present...

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Veröffentlicht in:	Oncology letters 2022-07, Vol.24 (1), p.221, Article 221
Hauptverfasser:	Imai, Toshio, Naruse, Mie, Ochiai, Masako, Matsumoto, Kenji, Ikeda, Satsuki, Kani, Manami, Kato, Yuyu, Hirayama, Akiyoshi, Soga, Tomoyoshi, Hori, Yusaku, Yokoi, Akira, Ochiai, Atsushi
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Body weight Cancer patients Colorectal cancer Ethics Experiments Fibroblasts Gene expression Genetic aspects Glucose metabolism Laboratories Metabolites Mortality Mutation Oncology Patients Protein binding
Online-Zugang:	Volltext
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