Cathepsin F and Fibulin-1 as novel diagnostic biomarkers for brain metastasis of non-small cell lung cancer

Background The lack of non-invasive methods for detection of early micro-metastasis is a major cause of the poor prognosis of non-small cell lung cancer (NSCLC) brain metastasis (BM) patients. Herein, we aimed to identify circulating biomarkers based on proteomics for the early diagnosis and monitor...

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Veröffentlicht in:	British journal of cancer 2022-06, Vol.126 (12), p.1795-1805
Hauptverfasser:	Wei, Song, Liu, Wenwen, Xu, Mingxin, Qin, Huamin, Liu, Chang, Zhang, Rui, Zhou, Sihai, Li, Encheng, Liu, Zhiyu, Wang, Qi
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1612/1350 692/4028/67/1612/1350 692/53/2421 692/53/2423 Animals Biomarkers Biomarkers, Tumor Biomedical and Life Sciences Biomedicine Brain cancer Brain Neoplasms - secondary Brain tumors Calcium-Binding Proteins Cancer Research Carcinoma, Non-Small-Cell Lung - pathology Cathepsin F Diagnosis Drug Resistance Epidemiology Humans Lung cancer Lung Neoplasms - pathology Magnetic resonance imaging Medical diagnosis Medical prognosis Metastases Metastasis Molecular Medicine Neuroimaging Non-small cell lung carcinoma Oncology Patients Prediction models Prognosis Proteomics Small cell lung carcinoma
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