Phosphaturic Mesenchymal Tumor

Phosphaturic mesenchymal tumors (PMTs) are neoplasms associated with tumor-induced osteomalacia. Patients typically present with pathologic fractures in the setting of chronic hypophosphatemic hyperphosphaturic osteomalacia, as well as gradual muscle weakness, bone pain, and difficulty walking. Beca...

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Veröffentlicht in:American journal of neuroradiology : AJNR 2022-06, Vol.43 (6), p.817-822
Hauptverfasser: Benson, J C, Trejo-Lopez, J A, Nassiri, A M, Eschbacher, K, Link, M J, Driscoll, C L, Tiegs, R D, Sfeir, J, DeLone, D R
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container_issue 6
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container_title American journal of neuroradiology : AJNR
container_volume 43
creator Benson, J C
Trejo-Lopez, J A
Nassiri, A M
Eschbacher, K
Link, M J
Driscoll, C L
Tiegs, R D
Sfeir, J
DeLone, D R
description Phosphaturic mesenchymal tumors (PMTs) are neoplasms associated with tumor-induced osteomalacia. Patients typically present with pathologic fractures in the setting of chronic hypophosphatemic hyperphosphaturic osteomalacia, as well as gradual muscle weakness, bone pain, and difficulty walking. Because of their rarity and nonspecific symptomatology, phosphaturic mesenchymal tumors often go undiagnosed for years. Even when discovered on imaging, the tumors can be diagnostically challenging for radiologists. Phosphaturic mesenchymal tumors often tend to be small and can be located nearly anywhere in the body, and, therefore, can mimic many other tumors. This case highlights the imaging and pathologic markers of a phosphaturic mesenchymal tumor, often found in a patient with tumor-induced osteomalacia.
doi_str_mv 10.3174/ajnr.A7513
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Head & Neck
Humans
Mesenchymoma - diagnosis
Mesenchymoma - diagnostic imaging
Neoplasms, Connective Tissue - diagnosis
Neoplasms, Connective Tissue - diagnostic imaging
Osteomalacia - diagnostic imaging
Osteomalacia - etiology
Paraneoplastic Syndromes - complications
Paraneoplastic Syndromes - diagnostic imaging
title Phosphaturic Mesenchymal Tumor
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