duper is a null mutation of Cryptochrome 1 in Syrian hamsters

The duper mutation is a recessive mutation that shortens the period length of the circadian rhythm in Syrian hamsters. These animals show a large phase shift when responding to light pulses. Limited genetic resources for the Syrian hamster (Mesocricetus auratus) presented a major obstacle to cloning...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2022-05, Vol.119 (18), p.1-8
Hauptverfasser:	Lee, Yin Yeng, Cal-Kayitmazbatir, Sibel, Francey, Lauren J., Bahiru, Michael Seifu, Hayer, Katharina E., Wu, Gang, Zeller, Molly J., Roberts, Robyn, Speers, James, Koshalek, Justin, Berres, Mark E., Bittman, Eric L., Hogenesch, John B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Assembly Biological clocks Biological Sciences Circadian rhythm Circadian Rhythm - genetics Circadian rhythms Cloning COVID-19 Cricetinae Cryptochromes Cryptochromes - genetics Ecotypes Gene mapping Genetic resources Genomes Hamsters Homozygosity Humans Loss of Function Mutation Medical research Mesocricetus Mutation Rodents Transcription Factors - genetics
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