A new form of axonal pathology in a spinal model of neuromyelitis optica

Neuromyelitis optica is a chronic neuroinflammatory disease, which primarily targets astrocytes and often results in severe axon injury of unknown mechanism. Neuromyelitis optica patients harbour autoantibodies against the astrocytic water channel protein, aquaporin-4 (AQP4-IgG), which induce comple...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2022-06, Vol.145 (5), p.1726-1742
Hauptverfasser:	Herwerth, Marina, Kenet, Selin, Schifferer, Martina, Winkler, Anne, Weber, Melanie, Snaidero, Nicolas, Wang, Mengzhe, Lohrberg, Melanie, Bennett, Jeffrey L, Stadelmann, Christine, Hemmer, Bernhard, Misgeld, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aquaporin 4 Astrocytes - metabolism Autoantibodies - metabolism Axons - pathology Humans Immunoglobulin G - metabolism Mice Neuromyelitis Optica - metabolism Original
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