Papillary Thyroid Cancer and a TERT Promotor Mutation-positive Paraganglioma in a Patient With a Germline SDHB Mutation

Abstract Purpose About 40% of paragangliomas (PGL) are due to germline mutations in one of several susceptibility genes. These genes rarely predispose to other non-PGL tumors. Here, we describe and functionally characterize a germline SDHB mutation in a patient who developed a BRAFV600E mutation-pos...

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Veröffentlicht in:	Journal of the Endocrine Society 2022-07, Vol.6 (7), p.bvac076-bvac076
Hauptverfasser:	Alzahrani, Ali S, Alswailem, Meshael, Murugan, Avaniyapuram Kannan, Alghamdi, Balgees, Al-Hindi, Hindi
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Clinical Development and progression Disease susceptibility Gene mutations Genetic aspects Genomics Metastasis PET imaging Telomerase Thyroid cancer
Online-Zugang:	Volltext
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