Feasibility of In Vivo Imaging of Fibroblast Activation Protein in Human Arterial Walls

Increased expression of fibroblast-activating protein (FAP) in fibrous caps may contribute to progression of atherosclerotic plaques. Forty-one patients who underwent Ga-conjugated quinoline-based FAP inhibitor ( Ga-FAPI-04) PET/CT for noncardiovascular indications were retrospectively analyzed. Cor...

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Veröffentlicht in:	Journal of Nuclear Medicine 2022-06, Vol.63 (6), p.948-951
Hauptverfasser:	Wu, Meiqi, Ning, Jing, Li, Jingle, Lai, Zhichao, Shi, Ximin, Xing, Haiqun, Hacker, Marcus, Liu, Bao, Huo, Li, Li, Xiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Arteriosclerosis Atherosclerosis Brief Communication Calcification Cardiovascular diseases Computed tomography Feasibility Studies Fibroblast activation protein Fibroblasts Gallium Radioisotopes Health risks Humans Medical imaging Plaques Positron emission Positron Emission Tomography Computed Tomography Proteins Quinoline Retrospective Studies Risk analysis Risk factors Tomography
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