The blood-brain barrier in aging and neurodegeneration

The blood-brain barrier (BBB) is vital for maintaining brain homeostasis by enabling an exquisite control of exchange of compounds between the blood and the brain parenchyma. Moreover, the BBB prevents unwanted toxins and pathogens from entering the brain. This barrier, however, breaks down with age...

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Veröffentlicht in:	Molecular psychiatry 2022-06, Vol.27 (6), p.2659-2673
Hauptverfasser:	Knox, Emily G., Aburto, Maria R., Clarke, Gerard, Cryan, John F., O’Driscoll, Caitriona M.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/154 631/378 Aging Behavioral Sciences Biological Psychology Blood-brain barrier Homeostasis Intestinal microflora Medicine Medicine & Public Health Metabolites Microbiota Neurodegeneration Neurosciences Parenchyma Pharmacotherapy Physiology Psychiatry Recovery of function Review Review Article
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