The Regulation and Characterization of Mitochondrial-Derived Methylmalonic Acid in Mitochondrial Dysfunction and Oxidative Stress: From Basic Research to Clinical Practice

Methylmalonic acid (MMA) can act as a diagnosis of hereditary methylmalonic acidemia and assess the status of vitamin B12. Moreover, as a new potential biomarker, it has been widely reported to be associated with the progression and prognosis of chronic diseases such as cardiovascular events, renal...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2022, Vol.2022, p.7043883-9
Hauptverfasser:	Liu, Yige, Wang, Shanjie, Zhang, Xiaoyuan, Cai, Hengxuan, Liu, Jinxin, Fang, Shaohong, Yu, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Metabolism, Inborn Errors - metabolism Biomarkers Cardiovascular disease Chronic illnesses DNA methylation Humans Methylmalonic Acid - metabolism Mitochondria - metabolism Oxidative Stress Review Vitamin B 12 Deficiency
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