Modified Trabeculectomy versus Glaucoma Drainage Implant Surgery: A Retrospective Comparative Study for Refractory Glaucoma Treatment
Purpose. To observe and compare the efficacy of modified trabeculectomy (TE), Ahmed drainage valve implantation (AGV), and EX-PRESS glaucoma shunt for refractory glaucoma (RG). Methods. The study population of this retrospective study comprised 73 patients (76 eyes) who were suffering from RG and tr...
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| Veröffentlicht in: | Oxidative medicine and cellular longevity 2022, Vol.2022, p.3050007-15 |
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| creator | He, Yuan He, Beilei Ji, Zhi Zhang, Ruixue Quan, Zhuoya Xie, Guijun Pu, Xiaoli |
| description | Purpose. To observe and compare the efficacy of modified trabeculectomy (TE), Ahmed drainage valve implantation (AGV), and EX-PRESS glaucoma shunt for refractory glaucoma (RG). Methods. The study population of this retrospective study comprised 73 patients (76 eyes) who were suffering from RG and treated with modified TE, AGV, and EX-PRESS glaucoma shunt in our hospital from October 2012 to October 2020. The number of cases who underwent modified TE, AVG, and EX-PRESS glaucoma shunt was 36 (38 eyes). 19 (20 eyes), and 18 patients (18 eyes), respectively. The intraocular pressure (IOP), best-corrected visual acuity (BCVA), postoperative antiglaucoma medications, filter bubble morphology, anterior chamber depth (ACD), successful rate, and postoperative complications were recorded and statistically analyzed preoperative and 1 d, 1 w, 1 mon, 3 mon, 6 mon, and the end follow-up after operation. Results. The BCVA differed insignificantly among the three cohorts before and 6 months after surgery. Compared to preoperative BCVA, the postoperative BCVA of the three groups had no statistical significance. An obvious reduction in IOP was observed in all the three group after operation (P |
| doi_str_mv | 10.1155/2022/3050007 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9150991</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2672702869</sourcerecordid><originalsourceid>FETCH-LOGICAL-c448t-9def1a2d27495866048cdba8805a91ec653afce226a0129897f7664e34c7fa203</originalsourceid><addsrcrecordid>eNp9kU1v1DAQhiMEoh9w44wscUFql_ojcWIOSNUCbaUiJLqcrVlnvHWVxKmdLMoP4H_j7S5L4cDJI_nx45l5s-wVo-8YK4ozTjk_E7SglJZPskOmcj6jSuVP9zWlB9lRjHeUSsFz9jw7EIUsWCnoYfbzi6-ddViTRYAlmrFBM_h2ImsMcYzkooHR-BbIxwCugxWSq7ZvoBvIzRhWGKb35Jx8wyH42KeXbo1k7tseAjzUN8NYT8T6kBgbIKnD9Me5CAhDi93wIntmoYn4cnceZ98_f1rML2fXXy-u5ufXM5Pn1TBTNVoGvOZlropKSppXpl5CVdECFEMjCwHWIOcSKOOqUqUtpcxR5Ka0wKk4zj5svf24bLE26esAje6DayFM2oPTf9907lav_ForVqSdsiR4uxMEfz9iHHTrosEmbQT9GDWXJS8pr6RK6Jt_0Ds_hi6Nt6EEF1yKDXW6pUzaYAxo980wqjf56k2-epdvwl8_HmAP_w40ASdb4NZ1Nfxw_9f9AvvKr2Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2673232639</pqid></control><display><type>article</type><title>Modified Trabeculectomy versus Glaucoma Drainage Implant Surgery: A Retrospective Comparative Study for Refractory Glaucoma Treatment</title><source>Wiley-Blackwell Open Access Collection</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>EZB Electronic Journals Library</source><source>PubMed Central Open Access</source><creator>He, Yuan ; He, Beilei ; Ji, Zhi ; Zhang, Ruixue ; Quan, Zhuoya ; Xie, Guijun ; Pu, Xiaoli</creator><contributor>Liang, Shao</contributor><creatorcontrib>He, Yuan ; He, Beilei ; Ji, Zhi ; Zhang, Ruixue ; Quan, Zhuoya ; Xie, Guijun ; Pu, Xiaoli ; Liang, Shao</creatorcontrib><description>Purpose. To observe and compare the efficacy of modified trabeculectomy (TE), Ahmed drainage valve implantation (AGV), and EX-PRESS glaucoma shunt for refractory glaucoma (RG). Methods. The study population of this retrospective study comprised 73 patients (76 eyes) who were suffering from RG and treated with modified TE, AGV, and EX-PRESS glaucoma shunt in our hospital from October 2012 to October 2020. The number of cases who underwent modified TE, AVG, and EX-PRESS glaucoma shunt was 36 (38 eyes). 19 (20 eyes), and 18 patients (18 eyes), respectively. The intraocular pressure (IOP), best-corrected visual acuity (BCVA), postoperative antiglaucoma medications, filter bubble morphology, anterior chamber depth (ACD), successful rate, and postoperative complications were recorded and statistically analyzed preoperative and 1 d, 1 w, 1 mon, 3 mon, 6 mon, and the end follow-up after operation. Results. The BCVA differed insignificantly among the three cohorts before and 6 months after surgery. Compared to preoperative BCVA, the postoperative BCVA of the three groups had no statistical significance. An obvious reduction in IOP was observed in all the three group after operation (P<0.05). An obvious decrease in antiglaucoma medications was observed after surgery in all the three groups (P<0.05). The AGV group showed deeper ACD postoperatively, while no marked difference was found in postoperative ACD in the other two groups. The total success rates in modified TE and AGV groups were slightly higher than those in the EX-PRESS group. The three groups differed insignificantly in filter bubble morphology after operation. Conclusion. Modified TE, AGV, and EX-PRESS glaucoma shunt showed equivalent efficacy for RG, which could validly reduce IOP and postoperative antiglaucoma medications. However, the success rates of modified TE and AGV were slightly higher than those of EX-PRESS glaucoma shunt in the last follow-up, and their complications were slightly less than those of the EX-PRESS glaucoma shunt.</description><identifier>ISSN: 1942-0900</identifier><identifier>EISSN: 1942-0994</identifier><identifier>DOI: 10.1155/2022/3050007</identifier><identifier>PMID: 35651730</identifier><language>eng</language><publisher>United States: Hindawi</publisher><subject>Diabetes ; Glaucoma ; Hypertension ; Inflammation ; Surgery ; Surgical outcomes ; Sutures ; Viscoelasticity</subject><ispartof>Oxidative medicine and cellular longevity, 2022, Vol.2022, p.3050007-15</ispartof><rights>Copyright © 2022 Yuan He et al.</rights><rights>Copyright © 2022 Yuan He et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2022 Yuan He et al. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c448t-9def1a2d27495866048cdba8805a91ec653afce226a0129897f7664e34c7fa203</citedby><cites>FETCH-LOGICAL-c448t-9def1a2d27495866048cdba8805a91ec653afce226a0129897f7664e34c7fa203</cites><orcidid>0000-0002-4115-0115 ; 0000-0001-7692-5577 ; 0000-0002-5933-8087 ; 0000-0002-4988-4922</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150991/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150991/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,4010,27900,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35651730$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Liang, Shao</contributor><creatorcontrib>He, Yuan</creatorcontrib><creatorcontrib>He, Beilei</creatorcontrib><creatorcontrib>Ji, Zhi</creatorcontrib><creatorcontrib>Zhang, Ruixue</creatorcontrib><creatorcontrib>Quan, Zhuoya</creatorcontrib><creatorcontrib>Xie, Guijun</creatorcontrib><creatorcontrib>Pu, Xiaoli</creatorcontrib><title>Modified Trabeculectomy versus Glaucoma Drainage Implant Surgery: A Retrospective Comparative Study for Refractory Glaucoma Treatment</title><title>Oxidative medicine and cellular longevity</title><addtitle>Oxid Med Cell Longev</addtitle><description>Purpose. To observe and compare the efficacy of modified trabeculectomy (TE), Ahmed drainage valve implantation (AGV), and EX-PRESS glaucoma shunt for refractory glaucoma (RG). Methods. The study population of this retrospective study comprised 73 patients (76 eyes) who were suffering from RG and treated with modified TE, AGV, and EX-PRESS glaucoma shunt in our hospital from October 2012 to October 2020. The number of cases who underwent modified TE, AVG, and EX-PRESS glaucoma shunt was 36 (38 eyes). 19 (20 eyes), and 18 patients (18 eyes), respectively. The intraocular pressure (IOP), best-corrected visual acuity (BCVA), postoperative antiglaucoma medications, filter bubble morphology, anterior chamber depth (ACD), successful rate, and postoperative complications were recorded and statistically analyzed preoperative and 1 d, 1 w, 1 mon, 3 mon, 6 mon, and the end follow-up after operation. Results. The BCVA differed insignificantly among the three cohorts before and 6 months after surgery. Compared to preoperative BCVA, the postoperative BCVA of the three groups had no statistical significance. An obvious reduction in IOP was observed in all the three group after operation (P<0.05). An obvious decrease in antiglaucoma medications was observed after surgery in all the three groups (P<0.05). The AGV group showed deeper ACD postoperatively, while no marked difference was found in postoperative ACD in the other two groups. The total success rates in modified TE and AGV groups were slightly higher than those in the EX-PRESS group. The three groups differed insignificantly in filter bubble morphology after operation. Conclusion. Modified TE, AGV, and EX-PRESS glaucoma shunt showed equivalent efficacy for RG, which could validly reduce IOP and postoperative antiglaucoma medications. However, the success rates of modified TE and AGV were slightly higher than those of EX-PRESS glaucoma shunt in the last follow-up, and their complications were slightly less than those of the EX-PRESS glaucoma shunt.</description><subject>Diabetes</subject><subject>Glaucoma</subject><subject>Hypertension</subject><subject>Inflammation</subject><subject>Surgery</subject><subject>Surgical outcomes</subject><subject>Sutures</subject><subject>Viscoelasticity</subject><issn>1942-0900</issn><issn>1942-0994</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kU1v1DAQhiMEoh9w44wscUFql_ojcWIOSNUCbaUiJLqcrVlnvHWVxKmdLMoP4H_j7S5L4cDJI_nx45l5s-wVo-8YK4ozTjk_E7SglJZPskOmcj6jSuVP9zWlB9lRjHeUSsFz9jw7EIUsWCnoYfbzi6-ddViTRYAlmrFBM_h2ImsMcYzkooHR-BbIxwCugxWSq7ZvoBvIzRhWGKb35Jx8wyH42KeXbo1k7tseAjzUN8NYT8T6kBgbIKnD9Me5CAhDi93wIntmoYn4cnceZ98_f1rML2fXXy-u5ufXM5Pn1TBTNVoGvOZlropKSppXpl5CVdECFEMjCwHWIOcSKOOqUqUtpcxR5Ka0wKk4zj5svf24bLE26esAje6DayFM2oPTf9907lav_ForVqSdsiR4uxMEfz9iHHTrosEmbQT9GDWXJS8pr6RK6Jt_0Ds_hi6Nt6EEF1yKDXW6pUzaYAxo980wqjf56k2-epdvwl8_HmAP_w40ASdb4NZ1Nfxw_9f9AvvKr2Q</recordid><startdate>2022</startdate><enddate>2022</enddate><creator>He, Yuan</creator><creator>He, Beilei</creator><creator>Ji, Zhi</creator><creator>Zhang, Ruixue</creator><creator>Quan, Zhuoya</creator><creator>Xie, Guijun</creator><creator>Pu, Xiaoli</creator><general>Hindawi</general><general>Hindawi Limited</general><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4115-0115</orcidid><orcidid>https://orcid.org/0000-0001-7692-5577</orcidid><orcidid>https://orcid.org/0000-0002-5933-8087</orcidid><orcidid>https://orcid.org/0000-0002-4988-4922</orcidid></search><sort><creationdate>2022</creationdate><title>Modified Trabeculectomy versus Glaucoma Drainage Implant Surgery: A Retrospective Comparative Study for Refractory Glaucoma Treatment</title><author>He, Yuan ; He, Beilei ; Ji, Zhi ; Zhang, Ruixue ; Quan, Zhuoya ; Xie, Guijun ; Pu, Xiaoli</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c448t-9def1a2d27495866048cdba8805a91ec653afce226a0129897f7664e34c7fa203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Diabetes</topic><topic>Glaucoma</topic><topic>Hypertension</topic><topic>Inflammation</topic><topic>Surgery</topic><topic>Surgical outcomes</topic><topic>Sutures</topic><topic>Viscoelasticity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>He, Yuan</creatorcontrib><creatorcontrib>He, Beilei</creatorcontrib><creatorcontrib>Ji, Zhi</creatorcontrib><creatorcontrib>Zhang, Ruixue</creatorcontrib><creatorcontrib>Quan, Zhuoya</creatorcontrib><creatorcontrib>Xie, Guijun</creatorcontrib><creatorcontrib>Pu, Xiaoli</creatorcontrib><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Oxidative medicine and cellular longevity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>He, Yuan</au><au>He, Beilei</au><au>Ji, Zhi</au><au>Zhang, Ruixue</au><au>Quan, Zhuoya</au><au>Xie, Guijun</au><au>Pu, Xiaoli</au><au>Liang, Shao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Modified Trabeculectomy versus Glaucoma Drainage Implant Surgery: A Retrospective Comparative Study for Refractory Glaucoma Treatment</atitle><jtitle>Oxidative medicine and cellular longevity</jtitle><addtitle>Oxid Med Cell Longev</addtitle><date>2022</date><risdate>2022</risdate><volume>2022</volume><spage>3050007</spage><epage>15</epage><pages>3050007-15</pages><issn>1942-0900</issn><eissn>1942-0994</eissn><abstract>Purpose. To observe and compare the efficacy of modified trabeculectomy (TE), Ahmed drainage valve implantation (AGV), and EX-PRESS glaucoma shunt for refractory glaucoma (RG). Methods. The study population of this retrospective study comprised 73 patients (76 eyes) who were suffering from RG and treated with modified TE, AGV, and EX-PRESS glaucoma shunt in our hospital from October 2012 to October 2020. The number of cases who underwent modified TE, AVG, and EX-PRESS glaucoma shunt was 36 (38 eyes). 19 (20 eyes), and 18 patients (18 eyes), respectively. The intraocular pressure (IOP), best-corrected visual acuity (BCVA), postoperative antiglaucoma medications, filter bubble morphology, anterior chamber depth (ACD), successful rate, and postoperative complications were recorded and statistically analyzed preoperative and 1 d, 1 w, 1 mon, 3 mon, 6 mon, and the end follow-up after operation. Results. The BCVA differed insignificantly among the three cohorts before and 6 months after surgery. Compared to preoperative BCVA, the postoperative BCVA of the three groups had no statistical significance. An obvious reduction in IOP was observed in all the three group after operation (P<0.05). An obvious decrease in antiglaucoma medications was observed after surgery in all the three groups (P<0.05). The AGV group showed deeper ACD postoperatively, while no marked difference was found in postoperative ACD in the other two groups. The total success rates in modified TE and AGV groups were slightly higher than those in the EX-PRESS group. The three groups differed insignificantly in filter bubble morphology after operation. Conclusion. Modified TE, AGV, and EX-PRESS glaucoma shunt showed equivalent efficacy for RG, which could validly reduce IOP and postoperative antiglaucoma medications. However, the success rates of modified TE and AGV were slightly higher than those of EX-PRESS glaucoma shunt in the last follow-up, and their complications were slightly less than those of the EX-PRESS glaucoma shunt.</abstract><cop>United States</cop><pub>Hindawi</pub><pmid>35651730</pmid><doi>10.1155/2022/3050007</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0002-4115-0115</orcidid><orcidid>https://orcid.org/0000-0001-7692-5577</orcidid><orcidid>https://orcid.org/0000-0002-5933-8087</orcidid><orcidid>https://orcid.org/0000-0002-4988-4922</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Diabetes Glaucoma Hypertension Inflammation Surgery Surgical outcomes Sutures Viscoelasticity |
| title | Modified Trabeculectomy versus Glaucoma Drainage Implant Surgery: A Retrospective Comparative Study for Refractory Glaucoma Treatment |
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