Histopathological and molecular links of COVID-19 with novel clinical manifestations for the management of coronavirus-like complications
Coronavirus disease 2019 (COVID-19) causes transmissible viral illness of the respiratory tract prompted by the SARS-CoV-2 virus. COVID-19 is one of the worst global pandemics affecting a large population worldwide and causing catastrophic loss of life. Patients having pre-existing chronic disorders...
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| Veröffentlicht in: | Inflammopharmacology 2022-08, Vol.30 (4), p.1219-1257 |
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| container_title | Inflammopharmacology |
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| creator | Sood, Ankita Bedi, Onkar |
| description | Coronavirus disease 2019 (COVID-19) causes transmissible viral illness of the respiratory tract prompted by the SARS-CoV-2 virus. COVID-19 is one of the worst global pandemics affecting a large population worldwide and causing catastrophic loss of life. Patients having pre-existing chronic disorders are more susceptible to contracting this viral infection. This pandemic virus is known to cause notable respiratory pathology. Besides, it can also cause extra-pulmonary manifestations. Multiple extra-pulmonary tissues express the SARS-CoV-2 entry receptor, hence causing direct viral tissue damage. This insightful review gives a brief description of the impact of coronavirus on the pulmonary system, extra-pulmonary systems, histopathology, multiorgan consequences, the possible mechanisms associated with the disease, and various potential therapeutic approaches to tackle the manifestations. |
| doi_str_mv | 10.1007/s10787-022-00999-9 |
| format | Article |
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| ispartof | Inflammopharmacology, 2022-08, Vol.30 (4), p.1219-1257 |
| issn | 0925-4692 1568-5608 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Allergology Biomedical and Life Sciences Biomedicine COVID-19 Dermatology Gastroenterology Humans Immunology Pandemics Pharmacology/Toxicology Review Rheumatology SARS-CoV-2 |
| title | Histopathological and molecular links of COVID-19 with novel clinical manifestations for the management of coronavirus-like complications |
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