Reduced Osteogenic Differentiation Potential In Vivo in Acute Myeloid Leukaemia Patients Correlates with Decreased BMP4 Expression in Mesenchymal Stromal Cells

The osteogenic differentiation potential of mesenchymal stromal cells (hMSCs) is an essential process for the haematopoiesis and the maintenance of haematopoietic stem cells (HSCs). Therefore, the aim of this work was to evaluate this potential in hMSCs from AML patients (hMSCs-AML) and whether it i...

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Veröffentlicht in:International Journal of Stem Cells 2022-05, Vol.15 (2), p.227-232
Hauptverfasser: Azevedo, Pedro L, Dias, Rhayra B, Nogueira, Liebert P, Maradei, Simone, Bigni, Ricardo, Aragao, Jordana S R, Abdelhay, Eliana, Binato, Renata
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Sprache:eng
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