Arylquin 1 (Potent Par-4 Secretagogue) Inhibits Tumor Progression and Induces Apoptosis in Colon Cancer Cells

Colorectal cancer (CRC) is one of the most common gastrointestinal cancers worldwide. Current therapeutic strategies mainly involve surgery and chemoradiotherapy; however, novel antitumor compounds are needed to avoid drug resistance in CRC, as well as the severe side effects of current treatments....

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Veröffentlicht in:	International journal of molecular sciences 2022-05, Vol.23 (10), p.5645
Hauptverfasser:	Chen, Yi-Ting, Tseng, Tzu-Ting, Tsai, Hung-Pei, Huang, Ming-Yii
Format:	Artikel
Sprache:	eng
Schlagworte:	Annexin V Apoptosis c-Jun protein Cadherin Cancer therapies Caspase-3 Cell adhesion & migration Cell proliferation Cell viability Chemoradiotherapy Chemotherapy Colon Colon cancer Colorectal cancer Colorectal carcinoma Cyclin D1 Cytotoxicity Drug dosages Drug resistance Extracellular signal-regulated kinase JNK protein Kinases Medical prognosis Metastasis N-Cadherin Phosphorylation Prostate Proteins Transcription factors Tumors Wound healing Xenografts Xenotransplantation
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