Effect of Progenitor Cell Mobilization With Granulocyte-Macrophage Colony-Stimulating Factor in Patients With Peripheral Artery Disease: A Randomized Clinical Trial

IMPORTANCE Many patients with peripheral artery disease (PAD) have walking impairment despite therapy. Experimental studies in animals demonstrate improved perfusion in ischemic hind limb after mobilization of bone marrow progenitor cells (PCs), but whether this is effective in patients with PAD is...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2013-12, Vol.310 (24), p.2631-2639
Hauptverfasser:	Poole, Joseph, Mavromatis, Kreton, Binongo, José N, Khan, Ali, Li, Qunna, Khayata, Mohamed, Rocco, Elizabeth, Topel, Matthew, Zhang, Xin, Brown, Charlene, Corriere, Matthew A, Murrow, Jonathan, Sher, Salman, Clement, Stephanie, Ashraf, Khuram, Rashed, Amr, Kabbany, Tarek, Neuman, Robert, Morris, Alanna, Ali, Arshad, Hayek, Salim, Oshinski, John, Yoon, Young-sup, Waller, Edmund K, Quyyumi, Arshed A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Double-Blind Method Exercise Test Female General aspects Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage Hematopoietic Stem Cell Mobilization Humans Injections, Subcutaneous Intermittent Claudication - therapy Male Medical sciences Middle Aged Peripheral Arterial Disease - therapy Stem Cells Treatment Outcome Walking
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