Interfering with CSE1L/CAS inhibits tumour growth via C3 in triple‐negative breast cancer

Triple‐negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. However, the treatment regimens for TNBC are limited. Chromosome segregation 1‐like (CSE1L), also called cellular apoptosis susceptibility protein (CAS), is highly expressed in breast cancer and plays a crucial rol...

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Veröffentlicht in:	Cell proliferation 2022-05, Vol.55 (5), p.e13226-n/a
Hauptverfasser:	Ye, Mei, Chen, Yufei, Liu, Jianni, Tian, Jiawei, Wang, Xunda, Fok, Kin Lam, Shi, Jianwu, Chen, Hao
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Breast - pathology Breast cancer Cell cycle Cell growth Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Cellular apoptosis susceptibility protein Cellular Apoptosis Susceptibility Protein - genetics Complement Complement C3 - metabolism Complement component C3 Gene expression Gene Expression Regulation, Neoplastic Humans Immune system Letter to the Editor Letters to the Editor Medical prognosis Metastases Metastasis Proteins Therapeutic targets Triple Negative Breast Neoplasms - pathology Tumors
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