Germline BRCA variants, lifestyle and ovarian cancer survival

Women with ovarian cancer who have a pathogenic germline variant in BRCA1 or BRCA2 (BRCA) have been shown to have better 5-year survival after diagnosis than women who are BRCA-wildtype (non-carriers). Modifiable lifestyle factors, including smoking, physical activity and body mass index (BMI) have...

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Veröffentlicht in:	Gynecologic oncology 2022-06, Vol.165 (3), p.437-445
Hauptverfasser:	Gersekowski, Kate, Delahunty, Rachel, Alsop, Kathryn, Goode, Ellen L., Cunningham, Julie M., Winham, Stacey J., Pharoah, Paul, Song, Honglin, Jordan, Susan, Fereday, Sian, DeFazio, Anna, Friedlander, Michael, Obermair, Andreas, Webb, Penelope M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Australia - epidemiology BRCA1 BRCA1 Protein - genetics BRCA2 BRCA2 Protein - genetics Carcinoma, Ovarian Epithelial - genetics Female Genes, BRCA1 Genes, BRCA2 Germ Cells Germ-Line Mutation Humans Life Style Lifestyle Ovarian cancer Ovarian Neoplasms - genetics Smoking Smoking - adverse effects Smoking - epidemiology Survival
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