Reverse Remodeling With Left Ventricular Assist Devices

This review provides a comprehensive overview of the past 25+ years of research into the development of left ventricular assist device (LVAD) to improve clinical outcomes in patients with severe end-stage heart failure and basic insights gained into the biology of heart failure gleaned from studies...

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Veröffentlicht in:	Circulation research 2021-05, Vol.128 (10), p.1594-1612
Hauptverfasser:	Burkhoff, Daniel, Topkara, Veli K., Sayer, Gabriel, Uriel, Nir
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Cell Death - physiology Cytokines - metabolism Cytoskeleton - physiology Disease Models, Animal Endothelial Cells - physiology Extracellular Matrix - physiology Heart Failure - therapy Heart-Assist Devices - adverse effects Heart-Assist Devices - trends Hemodynamics Humans Macrophages - cytology Mitochondria, Heart - physiology Myocardial Contraction Myocytes, Cardiac - physiology Transcriptome Ventricular Function, Left - physiology Ventricular Remodeling
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