Comparison of two T-cell assays to evaluate T-cell responses to SARS-CoV-2 following vaccination in naïve and convalescent healthcare workers

T-cell responses to SARS-CoV-2 following infection and vaccination are less characterized than antibody responses, due to a more complex experimental pathway. We measured T-cell responses in 108 healthcare workers (HCWs) using the commercialized Oxford Immunotec T-SPOT Discovery SARS-CoV-2 assay ser...

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Veröffentlicht in:	Clinical and experimental immunology 2022-07, Vol.209 (1), p.90-98
Hauptverfasser:	Phillips, Eloise, Adele, Sandra, Malone, Tom, Deeks, Alexandra, Stafford, Lizzie, Dobson, Susan L, Amini, Ali, Skelly, Donal, Eyre, David, Jeffery, Katie, Conlon, Christopher P, Dold, Christina, Otter, Ashley, D'Arcangelo, Silvia, Turtle, Lance, Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Viral BNT162 Vaccine - immunology ChAdOx1 nCoV-19 - immunology COVID-19 - prevention & control Health Personnel Humans Peptides SARS-CoV-2 Spike Glycoprotein, Coronavirus T-Lymphocytes - immunology Vaccination
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