Study on Hydration and Dehydration of Ezetimibe by Terahertz Spectroscopy with Humidity-Controlled Measurements and Theoretical Analysis

Understanding the solid-state transitions of active pharmaceutical ingredients (APIs) is essential for quality control since differences in their forms affect the bioavailability of APIs. Terahertz (THz) frequency-domain spectroscopy is suitable for such an application since it can sensitively probe...

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Veröffentlicht in:	The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory Molecules, spectroscopy, kinetics, environment, & general theory, 2022-05, Vol.126 (19), p.2879-2888
Hauptverfasser:	Mohara, Mizuki, Davis, Margaret P., Korter, Timothy M., Shimura, Kei, Ono, Touya, Aiko, Kenji
Format:	Artikel
Sprache:	eng
Schlagworte:	A: Structure, Spectroscopy, and Reactivity of Molecules and Clusters Dehydration Excipients - analysis Excipients - chemistry Ezetimibe Humans Humidity Tablets - chemistry Terahertz Spectroscopy - methods
Online-Zugang:	Volltext
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