Evaluating Estrogen Receptor Immunohistochemistry on Cell Blocks From Breast Cancer Patients in a Low-Resource Setting

Breast cancer biomarker assessment is critical in determining treatment and prognosis. In Tanzania, immunohistochemistry (IHC) is limited to surgical specimens and core biopsies. However, performing IHC on fine-needle aspiration biopsy cell blocks would offer numerous advantages. To compare the perf...

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Veröffentlicht in:	Archives of pathology & laboratory medicine (1976) 2021-07, Vol.145 (7), p.834-841
Hauptverfasser:	Kimambo, Asteria H, Vuhahula, Edda A, Mwakigonja, Amos R, Ljung, Britt-Marie, Zhang, Li, Van Loon, Katherine, Ng, Dianna L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers Biomarkers, Tumor - analysis Biopsy Biopsy, Fine-Needle Biopsy, Needle Breast cancer Breast carcinoma Breast Neoplasms - chemistry Breast Neoplasms - pathology Developing Countries Diagnosis Diagnostic immunohistochemistry Epidemiology Epidermal growth factor ErbB-2 protein Estrogen Estrogen receptors Estrogens Feasibility Studies Female Hospitals Humans Immunohistochemistry Laboratories Metastases Methods Middle Aged Monoclonal antibodies Observer Variation Paraffin Embedding Pathology Patients Predictive Value of Tests Progesterone Prospective Studies Receptors Receptors, Estrogen - analysis Reproducibility of Results San Francisco Tanzania Tissue Fixation
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