Precocious puberty: The clinical profile and the etiological classification of children presented at a tertiary care children's hospital
To determine the clinical spectrum and underlying etiologies of children presented with precocious puberty at The Children's Hospital &The Institute of Child health, Lahore. It is a retrospective review of all the children presented with precocious puberty over one year, from January 2015 t...
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| Veröffentlicht in: | Pakistan journal of medical sciences 2022-03, Vol.38 (4Part-II), p.955-959 |
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| creator | Aftab, Sommayya Manzoor, Jaida Mahmood, Qaiser Shaheen, Tahir |
| description | To determine the clinical spectrum and underlying etiologies of children presented with precocious puberty at The Children's Hospital &The Institute of Child health, Lahore.
It is a retrospective review of all the children presented with precocious puberty over one year, from January 2015 to December 2015; at the department of Paediatric Endocrinology & Diabetes, The Children's Hospital & The Institute of Child Health, Lahore.
Total 43 cases of precocious puberty (PP), with 26 females were reported in one year. Central precocious puberty (CPP) constituted 55.8% (24/43) and was found to be more prevalent in female (22/24). In 20/24 cases (83.3%) of central precocious puberty underlying etiology was idiopathic. Peripheral precocious puberty was found in 19/43 cases (44.1%) with male predominance (15/19). Congenital adrenal hyperplasia was the most frequent (12/19) underlying cause of peripheral precocious puberty in our cohort.
Precocious puberty could be a manifestation of underlying serious medical condition. It should be thoroughly evaluated with the aim to diagnose the underlying pathology and to treat them promptly. |
| doi_str_mv | 10.12669/pjms.38.4.4816 |
| format | Article |
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It is a retrospective review of all the children presented with precocious puberty over one year, from January 2015 to December 2015; at the department of Paediatric Endocrinology & Diabetes, The Children's Hospital & The Institute of Child Health, Lahore.
Total 43 cases of precocious puberty (PP), with 26 females were reported in one year. Central precocious puberty (CPP) constituted 55.8% (24/43) and was found to be more prevalent in female (22/24). In 20/24 cases (83.3%) of central precocious puberty underlying etiology was idiopathic. Peripheral precocious puberty was found in 19/43 cases (44.1%) with male predominance (15/19). Congenital adrenal hyperplasia was the most frequent (12/19) underlying cause of peripheral precocious puberty in our cohort.
Precocious puberty could be a manifestation of underlying serious medical condition. It should be thoroughly evaluated with the aim to diagnose the underlying pathology and to treat them promptly.</description><identifier>ISSN: 1682-024X</identifier><identifier>EISSN: 1681-715X</identifier><identifier>DOI: 10.12669/pjms.38.4.4816</identifier><identifier>PMID: 35634621</identifier><language>eng</language><publisher>Pakistan: Knowledge Bylanes</publisher><subject>Abdomen ; Age ; Atrophy ; Boys ; Brain tumors ; Children & youth ; Childrens health ; Diabetes ; Endocrinology ; Etiology ; Females ; Girls ; Hyperplasia ; Hypothyroidism ; Males ; Original ; Ovaries ; Pediatrics ; Physical growth ; Precocious puberty ; Puberty ; Steroids ; Testosterone ; Tumors</subject><ispartof>Pakistan journal of medical sciences, 2022-03, Vol.38 (4Part-II), p.955-959</ispartof><rights>Copyright: © Pakistan Journal of Medical Sciences.</rights><rights>COPYRIGHT 2022 Knowledge Bylanes</rights><rights>(c)2022 Pakistan Journal of Medical Sciences</rights><rights>Copyright: © Pakistan Journal of Medical Sciences 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c478t-ca9d542b25e91163511b2959e7817e7c1a487d3183db4170a22ead97d3e4ae523</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121963/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121963/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35634621$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aftab, Sommayya</creatorcontrib><creatorcontrib>Manzoor, Jaida</creatorcontrib><creatorcontrib>Mahmood, Qaiser</creatorcontrib><creatorcontrib>Shaheen, Tahir</creatorcontrib><title>Precocious puberty: The clinical profile and the etiological classification of children presented at a tertiary care children's hospital</title><title>Pakistan journal of medical sciences</title><addtitle>Pak J Med Sci</addtitle><description>To determine the clinical spectrum and underlying etiologies of children presented with precocious puberty at The Children's Hospital &The Institute of Child health, Lahore.
It is a retrospective review of all the children presented with precocious puberty over one year, from January 2015 to December 2015; at the department of Paediatric Endocrinology & Diabetes, The Children's Hospital & The Institute of Child Health, Lahore.
Total 43 cases of precocious puberty (PP), with 26 females were reported in one year. Central precocious puberty (CPP) constituted 55.8% (24/43) and was found to be more prevalent in female (22/24). In 20/24 cases (83.3%) of central precocious puberty underlying etiology was idiopathic. Peripheral precocious puberty was found in 19/43 cases (44.1%) with male predominance (15/19). Congenital adrenal hyperplasia was the most frequent (12/19) underlying cause of peripheral precocious puberty in our cohort.
Precocious puberty could be a manifestation of underlying serious medical condition. It should be thoroughly evaluated with the aim to diagnose the underlying pathology and to treat them promptly.</description><subject>Abdomen</subject><subject>Age</subject><subject>Atrophy</subject><subject>Boys</subject><subject>Brain tumors</subject><subject>Children & youth</subject><subject>Childrens health</subject><subject>Diabetes</subject><subject>Endocrinology</subject><subject>Etiology</subject><subject>Females</subject><subject>Girls</subject><subject>Hyperplasia</subject><subject>Hypothyroidism</subject><subject>Males</subject><subject>Original</subject><subject>Ovaries</subject><subject>Pediatrics</subject><subject>Physical growth</subject><subject>Precocious puberty</subject><subject>Puberty</subject><subject>Steroids</subject><subject>Testosterone</subject><subject>Tumors</subject><issn>1682-024X</issn><issn>1681-715X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNptkktv1DAQxyMEomXhzA1ZQgIuSeNn7B6QqoqXVAkORerN8jqTjVdOHOwsUr8BHxtnW5YuQj7YmvnN3_Mqipe4rjARQp1N2yFVVFasYhKLR8UpFhKXDeY3j_dvUtaE3ZwUz1La1jUTjJOnxQnlgjJB8Gnx61sEG6wLu4Sm3RrifHuOrntA1rvRWePRFEPnPCAztmjODphd8GGz91lvUnJdfmfjiEKHbO98G2HMYZBgnKFFZkYGzVnZmXiLrIlwoN4m1Ic0udn458WTzvgEL-7vVfH944fry8_l1ddPXy4vrkrLGjmX1qiWM7ImHBTGgnKM10RxBY3EDTQWGyablmJJ2zXDTW0IAdOqbAJmgBO6Kt7f6eZqB2htzjEar6fohpyeDsbpY8_oer0JP7XCBCtBs8C7e4EYfuwgzXpwyYL3ZoTcRU1Eg5USPLd4Vbz-B92GXRxzeZmSRNYsD_EvtTEetBu7kP-1i6i-EEpSrjiuM1X9h8qnhcHZMMIypOOANw8CejB-7lPwu2VS6Rg8uwNtDClF6A7NwLXeb5letkxTqZletixHvHrYwwP_Z63obzAPzxg</recordid><startdate>20220301</startdate><enddate>20220301</enddate><creator>Aftab, Sommayya</creator><creator>Manzoor, Jaida</creator><creator>Mahmood, Qaiser</creator><creator>Shaheen, Tahir</creator><general>Knowledge Bylanes</general><general>AsiaNet Pakistan (Pvt) Ltd</general><general>Professional Medical Publications</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220301</creationdate><title>Precocious puberty: The clinical profile and the etiological classification of children presented at a tertiary care children's hospital</title><author>Aftab, Sommayya ; Manzoor, Jaida ; Mahmood, Qaiser ; Shaheen, Tahir</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c478t-ca9d542b25e91163511b2959e7817e7c1a487d3183db4170a22ead97d3e4ae523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Abdomen</topic><topic>Age</topic><topic>Atrophy</topic><topic>Boys</topic><topic>Brain tumors</topic><topic>Children & youth</topic><topic>Childrens health</topic><topic>Diabetes</topic><topic>Endocrinology</topic><topic>Etiology</topic><topic>Females</topic><topic>Girls</topic><topic>Hyperplasia</topic><topic>Hypothyroidism</topic><topic>Males</topic><topic>Original</topic><topic>Ovaries</topic><topic>Pediatrics</topic><topic>Physical growth</topic><topic>Precocious puberty</topic><topic>Puberty</topic><topic>Steroids</topic><topic>Testosterone</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aftab, Sommayya</creatorcontrib><creatorcontrib>Manzoor, Jaida</creatorcontrib><creatorcontrib>Mahmood, Qaiser</creatorcontrib><creatorcontrib>Shaheen, Tahir</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Pakistan journal of medical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aftab, Sommayya</au><au>Manzoor, Jaida</au><au>Mahmood, Qaiser</au><au>Shaheen, Tahir</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Precocious puberty: The clinical profile and the etiological classification of children presented at a tertiary care children's hospital</atitle><jtitle>Pakistan journal of medical sciences</jtitle><addtitle>Pak J Med Sci</addtitle><date>2022-03-01</date><risdate>2022</risdate><volume>38</volume><issue>4Part-II</issue><spage>955</spage><epage>959</epage><pages>955-959</pages><issn>1682-024X</issn><eissn>1681-715X</eissn><abstract>To determine the clinical spectrum and underlying etiologies of children presented with precocious puberty at The Children's Hospital &The Institute of Child health, Lahore.
It is a retrospective review of all the children presented with precocious puberty over one year, from January 2015 to December 2015; at the department of Paediatric Endocrinology & Diabetes, The Children's Hospital & The Institute of Child Health, Lahore.
Total 43 cases of precocious puberty (PP), with 26 females were reported in one year. Central precocious puberty (CPP) constituted 55.8% (24/43) and was found to be more prevalent in female (22/24). In 20/24 cases (83.3%) of central precocious puberty underlying etiology was idiopathic. Peripheral precocious puberty was found in 19/43 cases (44.1%) with male predominance (15/19). Congenital adrenal hyperplasia was the most frequent (12/19) underlying cause of peripheral precocious puberty in our cohort.
Precocious puberty could be a manifestation of underlying serious medical condition. It should be thoroughly evaluated with the aim to diagnose the underlying pathology and to treat them promptly.</abstract><cop>Pakistan</cop><pub>Knowledge Bylanes</pub><pmid>35634621</pmid><doi>10.12669/pjms.38.4.4816</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| source | DOAJ Directory of Open Access Journals; PubMed Central Open Access; PubMed Central; Alma/SFX Local Collection |
| subjects | Abdomen Age Atrophy Boys Brain tumors Children & youth Childrens health Diabetes Endocrinology Etiology Females Girls Hyperplasia Hypothyroidism Males Original Ovaries Pediatrics Physical growth Precocious puberty Puberty Steroids Testosterone Tumors |
| title | Precocious puberty: The clinical profile and the etiological classification of children presented at a tertiary care children's hospital |
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