Endothelin‐1 potentiates TRPV1‐mediated vasoconstriction of human adipose arterioles in a protein kinase C‐dependent manner

Background and Purpose The TRPV cation channels have emerged as important regulators of vascular tone. TRPV1 channels and endothelin‐1 are independently associated with the pathophysiology of coronary vasospasm, but the relationship between their vasomotor functions remains unclear. We characterized...

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Veröffentlicht in:British journal of pharmacology 2021-02, Vol.178 (3), p.709-725
Hauptverfasser: Korishettar, Ankush M., Nishijima, Yoshinori, Wang, Zhihao, Xie, Yangjing, Fang, Juan, Wilcox, David A., Zhang, David X.
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Sprache:eng
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