Evaluation of the Sensitivity of Metabolic Profiling by Rapid Evaporative Ionization Mass Spectrometry: Toward More Radical Oral Cavity Cancer Resections

Radical resection for patients with oral cavity cancer remains challenging. Rapid evaporative ionization mass spectrometry (REIMS) of electrosurgical vapors has been reported for real-time classification of normal and tumor tissues for numerous surgical applications. However, the infiltrative patter...

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Veröffentlicht in:	Analytical chemistry (Washington) 2022-05, Vol.94 (19), p.6939-6947
Hauptverfasser:	Vaysse, Pierre-Maxence, Demers, Imke, van den Hout, Mari F. C. M., van de Worp, Wouter, Anthony, Ian G. M., Baijens, Laura W. J., Tan, Bing I., Lacko, Martin, Vaassen, Lauretta A. A., van Mierlo, Auke, Langen, Ramon C. J., Speel, Ernst-Jan M., Heeren, Ron M. A., Porta Siegel, Tiffany, Kremer, Bernd
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Cancer Cancer surgery Chemistry Cholesterol Classification Evaluation Head & neck cancer Heterogeneity Histopathology Humans Ionization Ions Keratinocytes Mass spectrometry Mass Spectrometry - methods Mass spectroscopy Metabolism Metabolomics Mixtures Mouth Neoplasms - surgery Mucosa Multivariate Analysis Myoblasts Oral cancer Oral carcinoma Oral cavity Oral squamous cell carcinoma Patients Phosphatidylethanolamine Scientific imaging Sensitivity analysis Soft tissues Spectrometry, Mass, Electrospray Ionization - methods Spectroscopy Squamous cell carcinoma Surgery Tissues Tumor cell lines Tumor cells Tumors Vapors
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