Neoadjuvant chemotherapy with or without radiotherapy versus upfront surgery for resectable pancreatic adenocarcinoma: a meta-analysis of randomized clinical trials

The role of neoadjuvant chemotherapy (NC) in resectable pancreatic cancer (RPC) has yet to be defined. This review aims to analyze the benefit of NC in RPC compared with upfront surgery (US) in terms of overall survival (OS) and disease-free survival (DFS). PubMed, CENTRAL (The Cochrane Library), an...

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Veröffentlicht in:	ESMO open 2022-06, Vol.7 (3), p.100485, Article 100485
Hauptverfasser:	Ghanem, I., Lora, D., Herradón, N., de Velasco, G., Carretero-González, A., Jiménez-Varas, M.Á., Vázquez de Parga, P., Feliu, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Humans meta-analysis neoadjuvant Neoadjuvant Therapy - methods Pancreatic Neoplasms Pancreatic Neoplasms - drug therapy randomized clinical trials Randomized Controlled Trials as Topic resectable pancreatic cancer Review upfront surgery
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