Prevalence of Hypertension in Sudanese Patients With Gouty Arthritis
Background In this study, we aimed to study the frequency of hypertension in Sudanese patients with gouty arthritis attending the largest three tertiary hospitals in Khartoum and correlate it with serum uric acid levels. Methodology An observational, descriptive, cross-sectional, hospital-based stud...
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creator | Khaild, Sufian M Fagir, Amro M Taha, Ziryab I Elshareef, Awadelkareem A Mohammed, Mohammed H Saeed, Khalda M Elagib, Elnour M Ibrahim, Elwalied M William, Jimmy |
description | Background In this study, we aimed to study the frequency of hypertension in Sudanese patients with gouty arthritis attending the largest three tertiary hospitals in Khartoum and correlate it with serum uric acid levels. Methodology An observational, descriptive, cross-sectional, hospital-based study was conducted in rheumatology clinics in Khartoum state, Sudan, from August 2020 to January 2021 involving 100 participants. Data were collected, prepared, and analyzed using SPSS version 25.0 (IBM Corp., Armonk, NY, USA). Results In this study, 100 participants were enrolled. The majority were males (79%), with 45% of the participants in the age group of 61-75 years. Overall, 89% of participants had symptoms of gouty arthritis, with the knee being the most common joint affected in 27% of participants. Most participants had a uric acid level above the target (6 mg/dL). The most frequently used uric acid lowering agent was found to be allopurinol in 85% of the patients. Furthermore, among those with gouty arthritis, 51% had hypertension with nearly half being insufficiently controlled. The frequency of undiagnosed hypertension among the participants was found to be 19%, which was statistically significant among gouty arthritis patients (p-value < 0.0001). Upon further analysis of our hypertensive participants, 79.5% of males (n = 35) had high blood pressure levels, which was statistically significant as well (p-value = 0.005), with the highest prevalence being among the age group of 61-75 years. Of those who were hypertensive, 51% had a history of concomitant comorbidity. Overall, 90% of the hypertensive participants (n = 40) had joint symptoms. Moreover, serum uric acid level was above the target in 93% of the participants. Conclusions Hypertension was found to be the most frequently recognized comorbidity in gouty arthritic patients, with more than a third remaining undiagnosed. Moreover, the male gender was a significant risk factor for hypertension among the gouty arthritis participants. Nevertheless, most patients with high blood pressure levels had concurrent elevated uric acid levels. |
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Methodology An observational, descriptive, cross-sectional, hospital-based study was conducted in rheumatology clinics in Khartoum state, Sudan, from August 2020 to January 2021 involving 100 participants. Data were collected, prepared, and analyzed using SPSS version 25.0 (IBM Corp., Armonk, NY, USA). Results In this study, 100 participants were enrolled. The majority were males (79%), with 45% of the participants in the age group of 61-75 years. Overall, 89% of participants had symptoms of gouty arthritis, with the knee being the most common joint affected in 27% of participants. Most participants had a uric acid level above the target (6 mg/dL). The most frequently used uric acid lowering agent was found to be allopurinol in 85% of the patients. Furthermore, among those with gouty arthritis, 51% had hypertension with nearly half being insufficiently controlled. The frequency of undiagnosed hypertension among the participants was found to be 19%, which was statistically significant among gouty arthritis patients (p-value < 0.0001). Upon further analysis of our hypertensive participants, 79.5% of males (n = 35) had high blood pressure levels, which was statistically significant as well (p-value = 0.005), with the highest prevalence being among the age group of 61-75 years. Of those who were hypertensive, 51% had a history of concomitant comorbidity. Overall, 90% of the hypertensive participants (n = 40) had joint symptoms. Moreover, serum uric acid level was above the target in 93% of the participants. Conclusions Hypertension was found to be the most frequently recognized comorbidity in gouty arthritic patients, with more than a third remaining undiagnosed. Moreover, the male gender was a significant risk factor for hypertension among the gouty arthritis participants. Nevertheless, most patients with high blood pressure levels had concurrent elevated uric acid levels.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.24248</identifier><identifier>PMID: 35602803</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Age groups ; Blood pressure ; Cardiovascular disease ; Comorbidity ; Coronaviruses ; COVID-19 ; Data collection ; Diabetes ; Females ; Hypertension ; Internal Medicine ; Males ; Metabolic syndrome ; Osteoarthritis ; Population ; Questionnaires ; Rheumatism ; Rheumatoid arthritis ; Rheumatology ; Teaching hospitals ; Uric acid</subject><ispartof>Curēus (Palo Alto, CA), 2022-04, Vol.14 (4), p.e24248-e24248</ispartof><rights>Copyright © 2022, Khaild et al.</rights><rights>Copyright © 2022, Khaild et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2022, Khaild et al. 2022 Khaild et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c299t-e80ae5661a4bb3a5eb1857b6c17d81661eaefacbe66618055ad3ecb2f6cf153c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116687/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116687/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27922,27923,53789,53791</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35602803$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Khaild, Sufian M</creatorcontrib><creatorcontrib>Fagir, Amro M</creatorcontrib><creatorcontrib>Taha, Ziryab I</creatorcontrib><creatorcontrib>Elshareef, Awadelkareem A</creatorcontrib><creatorcontrib>Mohammed, Mohammed H</creatorcontrib><creatorcontrib>Saeed, Khalda M</creatorcontrib><creatorcontrib>Elagib, Elnour M</creatorcontrib><creatorcontrib>Ibrahim, Elwalied M</creatorcontrib><creatorcontrib>William, Jimmy</creatorcontrib><title>Prevalence of Hypertension in Sudanese Patients With Gouty Arthritis</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Background In this study, we aimed to study the frequency of hypertension in Sudanese patients with gouty arthritis attending the largest three tertiary hospitals in Khartoum and correlate it with serum uric acid levels. Methodology An observational, descriptive, cross-sectional, hospital-based study was conducted in rheumatology clinics in Khartoum state, Sudan, from August 2020 to January 2021 involving 100 participants. Data were collected, prepared, and analyzed using SPSS version 25.0 (IBM Corp., Armonk, NY, USA). Results In this study, 100 participants were enrolled. The majority were males (79%), with 45% of the participants in the age group of 61-75 years. Overall, 89% of participants had symptoms of gouty arthritis, with the knee being the most common joint affected in 27% of participants. Most participants had a uric acid level above the target (6 mg/dL). The most frequently used uric acid lowering agent was found to be allopurinol in 85% of the patients. Furthermore, among those with gouty arthritis, 51% had hypertension with nearly half being insufficiently controlled. The frequency of undiagnosed hypertension among the participants was found to be 19%, which was statistically significant among gouty arthritis patients (p-value < 0.0001). Upon further analysis of our hypertensive participants, 79.5% of males (n = 35) had high blood pressure levels, which was statistically significant as well (p-value = 0.005), with the highest prevalence being among the age group of 61-75 years. Of those who were hypertensive, 51% had a history of concomitant comorbidity. Overall, 90% of the hypertensive participants (n = 40) had joint symptoms. Moreover, serum uric acid level was above the target in 93% of the participants. Conclusions Hypertension was found to be the most frequently recognized comorbidity in gouty arthritic patients, with more than a third remaining undiagnosed. Moreover, the male gender was a significant risk factor for hypertension among the gouty arthritis participants. Nevertheless, most patients with high blood pressure levels had concurrent elevated uric acid levels.</description><subject>Age groups</subject><subject>Blood pressure</subject><subject>Cardiovascular disease</subject><subject>Comorbidity</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Data collection</subject><subject>Diabetes</subject><subject>Females</subject><subject>Hypertension</subject><subject>Internal Medicine</subject><subject>Males</subject><subject>Metabolic syndrome</subject><subject>Osteoarthritis</subject><subject>Population</subject><subject>Questionnaires</subject><subject>Rheumatism</subject><subject>Rheumatoid arthritis</subject><subject>Rheumatology</subject><subject>Teaching hospitals</subject><subject>Uric acid</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkc1LAzEQxYMottTePEvAiwe3Jtmv7EUoVVuhYEHFY8imszZlu6lJttD_3mirVE8zzPx4vMdD6JySQZ6nxY1qLbRuwBKW8CPUZTTjEac8OT7YO6jv3JIQQknOSE5OUSdOM8I4ibvobmZhI2toFGBT4cl2DdZD47RpsG7wczuXDTjAM-k1NN7hN-0XeGxav8VD6xdWe-3O0Eklawf9_eyh14f7l9Ekmj6NH0fDaaRYUfgIOJGQZhmVSVnGMoWS8jQvM0XzOafhDhIqqUrIws5Jmsp5DKpkVaYqmsYq7qHbne66LVcwV8GQlbVYW72SdiuM1OLvp9EL8W42oqBBnudB4GovYM1HC86LlXYK6jqENK0TLFCMFgkjAb38hy5Na5sQL1A5DWLBZaCud5SyxjkL1a8ZSsRXQ2LXkPhuKOAXhwF-4Z8-4k8XtY57</recordid><startdate>20220418</startdate><enddate>20220418</enddate><creator>Khaild, Sufian M</creator><creator>Fagir, Amro M</creator><creator>Taha, Ziryab I</creator><creator>Elshareef, Awadelkareem A</creator><creator>Mohammed, Mohammed H</creator><creator>Saeed, Khalda M</creator><creator>Elagib, Elnour M</creator><creator>Ibrahim, Elwalied M</creator><creator>William, Jimmy</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220418</creationdate><title>Prevalence of Hypertension in Sudanese Patients With Gouty Arthritis</title><author>Khaild, Sufian M ; Fagir, Amro M ; Taha, Ziryab I ; Elshareef, Awadelkareem A ; Mohammed, Mohammed H ; Saeed, Khalda M ; Elagib, Elnour M ; Ibrahim, Elwalied M ; William, Jimmy</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c299t-e80ae5661a4bb3a5eb1857b6c17d81661eaefacbe66618055ad3ecb2f6cf153c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Age groups</topic><topic>Blood pressure</topic><topic>Cardiovascular disease</topic><topic>Comorbidity</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Data collection</topic><topic>Diabetes</topic><topic>Females</topic><topic>Hypertension</topic><topic>Internal Medicine</topic><topic>Males</topic><topic>Metabolic syndrome</topic><topic>Osteoarthritis</topic><topic>Population</topic><topic>Questionnaires</topic><topic>Rheumatism</topic><topic>Rheumatoid arthritis</topic><topic>Rheumatology</topic><topic>Teaching hospitals</topic><topic>Uric acid</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khaild, Sufian M</creatorcontrib><creatorcontrib>Fagir, Amro M</creatorcontrib><creatorcontrib>Taha, Ziryab I</creatorcontrib><creatorcontrib>Elshareef, Awadelkareem A</creatorcontrib><creatorcontrib>Mohammed, Mohammed H</creatorcontrib><creatorcontrib>Saeed, Khalda M</creatorcontrib><creatorcontrib>Elagib, Elnour M</creatorcontrib><creatorcontrib>Ibrahim, Elwalied M</creatorcontrib><creatorcontrib>William, Jimmy</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khaild, Sufian M</au><au>Fagir, Amro M</au><au>Taha, Ziryab I</au><au>Elshareef, Awadelkareem A</au><au>Mohammed, Mohammed H</au><au>Saeed, Khalda M</au><au>Elagib, Elnour M</au><au>Ibrahim, Elwalied M</au><au>William, Jimmy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of Hypertension in Sudanese Patients With Gouty Arthritis</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2022-04-18</date><risdate>2022</risdate><volume>14</volume><issue>4</issue><spage>e24248</spage><epage>e24248</epage><pages>e24248-e24248</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Background In this study, we aimed to study the frequency of hypertension in Sudanese patients with gouty arthritis attending the largest three tertiary hospitals in Khartoum and correlate it with serum uric acid levels. Methodology An observational, descriptive, cross-sectional, hospital-based study was conducted in rheumatology clinics in Khartoum state, Sudan, from August 2020 to January 2021 involving 100 participants. Data were collected, prepared, and analyzed using SPSS version 25.0 (IBM Corp., Armonk, NY, USA). Results In this study, 100 participants were enrolled. The majority were males (79%), with 45% of the participants in the age group of 61-75 years. Overall, 89% of participants had symptoms of gouty arthritis, with the knee being the most common joint affected in 27% of participants. Most participants had a uric acid level above the target (6 mg/dL). The most frequently used uric acid lowering agent was found to be allopurinol in 85% of the patients. Furthermore, among those with gouty arthritis, 51% had hypertension with nearly half being insufficiently controlled. The frequency of undiagnosed hypertension among the participants was found to be 19%, which was statistically significant among gouty arthritis patients (p-value < 0.0001). Upon further analysis of our hypertensive participants, 79.5% of males (n = 35) had high blood pressure levels, which was statistically significant as well (p-value = 0.005), with the highest prevalence being among the age group of 61-75 years. Of those who were hypertensive, 51% had a history of concomitant comorbidity. Overall, 90% of the hypertensive participants (n = 40) had joint symptoms. Moreover, serum uric acid level was above the target in 93% of the participants. Conclusions Hypertension was found to be the most frequently recognized comorbidity in gouty arthritic patients, with more than a third remaining undiagnosed. Moreover, the male gender was a significant risk factor for hypertension among the gouty arthritis participants. Nevertheless, most patients with high blood pressure levels had concurrent elevated uric acid levels.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>35602803</pmid><doi>10.7759/cureus.24248</doi><oa>free_for_read</oa></addata></record> |
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subjects | Age groups Blood pressure Cardiovascular disease Comorbidity Coronaviruses COVID-19 Data collection Diabetes Females Hypertension Internal Medicine Males Metabolic syndrome Osteoarthritis Population Questionnaires Rheumatism Rheumatoid arthritis Rheumatology Teaching hospitals Uric acid |
title | Prevalence of Hypertension in Sudanese Patients With Gouty Arthritis |
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