Scaffold hopping by net photochemical carbon deletion of azaarenes

Discovery chemists routinely identify purpose-tailored molecules through an iterative structural optimization approach, but the preparation of each successive candidate in a compound series can rarely be conducted in a manner matching their thought process. This is because many of the necessary chem...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2022-04, Vol.376 (6592), p.527-532
Hauptverfasser:	Woo, Jisoo, Christian, Alec H, Burgess, Samantha A, Jiang, Yuan, Mansoor, Umar Faruk, Levin, Mark D
Format:	Artikel
Sprache:	eng
Schlagworte:	Broadband Carbon Indoles Irradiation N-Oxides Organic compounds Photochemicals Quinoline Quinolines
Online-Zugang:	Volltext
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