DNA Methylation Regulates a Set of Long Non-Coding RNAs Compromising Hepatic Identity during Hepatocarcinogenesis

Long noncoding RNAs (lncRNAs) are emerging as key players in cancer, including hepatocellular carcinoma (HCC). Here we identify the mechanism implicated in the HCC inhibition of a set of lncRNAs, and their contribution to the process of hepatocarcinogenesis. The top-ranked 35 lncRNAs downregulated i...

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Veröffentlicht in:	Cancers 2022-04, Vol.14 (9), p.2048
Hauptverfasser:	Recalde, Miriam, Gárate-Rascón, María, Herranz, José María, Elizalde, María, Azkona, María, Unfried, Juan P, Boix, Loreto, Reig, María, Sangro, Bruno, Fernández-Barrena, Maite G, Fortes, Puri, Ávila, Matías A, Berasain, Carmen, Arechederra, María
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Cell differentiation DNA methylation Epigenetics Fetuses Gene expression Genomes Hepatocellular carcinoma Hepatocytes Liver cancer Non-coding RNA Patients Prognosis Therapeutic targets Tumors
Online-Zugang:	Volltext
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