Properties of the epileptiform activity in the cingulate cortex of a mouse model of LIS1 dysfunction

Dysfunction of the LIS1 gene causes lissencephaly, a drastic neurological disorder characterized by a deep disruption of the cortical structure. We aim to uncover alterations of the cortical neuronal networks related with the propagation of epileptiform activity in the Lis1/sLis1 mouse, a model lack...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain Structure and Function 2022-06, Vol.227 (5), p.1599-1614
Hauptverfasser:	Domínguez-Sala, E., Andreu-Cervera, A., Martín-Climent, P., Murcia-Ramón, R., Martínez, S., Geijo-Barrientos, Emilio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal memory Bicuculline Biomedical and Life Sciences Biomedicine Brain slice preparation Cell Biology Cortex (cingulate) Epilepsy Excitatory postsynaptic potentials Firing pattern LIS1 protein Lissencephaly Neural networks Neurology Neurosciences Original Original Article Propagation Pyramidal cells α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors γ-Aminobutyric acid A receptors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!