The Tails of Protein Kinase A

Protein kinase A (PKA) is a holoenzyme consisting of a regulatory (R)-subunit dimer and two catalytic (C)-subunits. There are two major families of C-subunits, Cα and Cβ, and four functionally nonredundant R-subunits (RIα, RIβ, RIIα, RIIβ). In addition to binding to and being regulated by the R-subu...

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Veröffentlicht in:	Molecular pharmacology 2022-04, Vol.101 (4), p.219-225
Hauptverfasser:	Taylor, Susan S., Søberg, Kristoffer, Kobori, Evan, Wu, Jian, Pautz, Sabine, Herberg, Friedrich W., Skålhegg, Bjørn Steen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axelrod Symposium Protein Kinases in Tune - Special Section brain cAMP-dependent protein kinase Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - genetics Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - metabolism Cyclic AMP-Dependent Protein Kinases - metabolism family Humans mitochondria pharmacology Protein Isoforms - metabolism protein kinase C Protein Kinases - metabolism retina Signal Transduction subfamily
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