Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones
A simple, mild, catalytic and efficient method for the straightforward synthesis of an interesting class of 2-aryl/alkyl-substituted-3-indolyl quinones in good to high yields is reported for the first time. This atom-efficient method proceeds copper-catalyzed one-pot sequential intramolecular hydroa...
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| Veröffentlicht in: | RSC advances 2018-01, Vol.8 (39), p.22122-22126 |
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| container_end_page | 22126 |
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| container_issue | 39 |
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| container_title | RSC advances |
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| creator | Jillella, Raveendra Oh, Chang Ho |
| description | A simple, mild, catalytic and efficient method for the straightforward synthesis of an interesting class of 2-aryl/alkyl-substituted-3-indolyl quinones in good to high yields is reported for the first time. This atom-efficient method proceeds
copper-catalyzed one-pot sequential intramolecular hydroamination (C-N bond formation) of 2-alkynylanilines followed by oxidative C-C coupling with benzoquinones. |
| doi_str_mv | 10.1039/c8ra03712d |
| format | Article |
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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central |
| subjects | Aromatic compounds Cascade chemical reactions Catalysis Chemical synthesis Chemistry Copper Quinones |
| title | Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones |
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