Promising bactericidal approach of dihydrazone analogues against bio-film forming Gram-negative bacteria and molecular mechanistic studies

Gram-negative members of the ESCAPE family are more difficult to treat, due to the presence of an additional barrier in the form of a lipopolysaccharide layer and the efficiency of efflux pumps to pump out the drugs from the cytoplasm. The development of alternative therapeutic strategies to tackle...

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Veröffentlicht in:RSC advances 2018-01, Vol.8 (10), p.5473-5483
Hauptverfasser: Rakesh, K P, Vivek, H K, Manukumar, H M, Shantharam, C S, Bukhari, S N A, Qin, Hua-Li, Sridhara, M B
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Sprache:eng
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