Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones

A novel route for the synthesis of 2-arylated quinolines through a [5 + 1] annulation directly from 2-methylquinolines and diynones under catalyst-free and solvent-free conditions was disclosed. This synthetic process was atom-economic, with good tolerance of a broad range of functional groups, and...

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Veröffentlicht in:RSC advances 2018-01, Vol.8 (9), p.4584-4587
Hauptverfasser: Zhao, Hai-Yuan, Wu, Fu-Song, Yang, Li, Liang, Ying, Cao, Xiao-Lin, Wang, Heng-Shan, Pan, Ying-Ming
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container_end_page 4587
container_issue 9
container_start_page 4584
container_title RSC advances
container_volume 8
creator Zhao, Hai-Yuan
Wu, Fu-Song
Yang, Li
Liang, Ying
Cao, Xiao-Lin
Wang, Heng-Shan
Pan, Ying-Ming
description A novel route for the synthesis of 2-arylated quinolines through a [5 + 1] annulation directly from 2-methylquinolines and diynones under catalyst-free and solvent-free conditions was disclosed. This synthetic process was atom-economic, with good tolerance of a broad range of functional groups, and with great practical worth.
doi_str_mv 10.1039/c7ra12716b
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subjects Catalysis
Catalysts
Chemical reactions
Chemistry
Functional groups
Organic chemistry
Organic compounds
Solvents
title Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones
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