Handgrip strength predicts length of hospital stay in an abdominal surgical setting: the role of frailty beyond age
Background Chronological age per se cannot be considered a prognostic risk factor for outcomes after elective surgery, whereas frailty could be. A simple and easy-to-get marker for frailty, such as handgrip strength (HGS), may support the surgeon in decision for an adequate healthcare plan. Aims The...
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| Veröffentlicht in: | Aging clinical and experimental research 2022-04, Vol.34 (4), p.811-817 |
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| creator | Marano, Luigi Carbone, Ludovico Poto, Gianmario Edoardo Gambelli, Margherita Nguefack Noudem, Leonelle Lore Grassi, Giulia Manasci, Fabiana Curreri, Giulia Giuliani, Alessandra Piagnerelli, Riccardo Savelli, Vinno Marrelli, Daniele Roviello, Franco Boccardi, Virginia |
| description | Background
Chronological age per se cannot be considered a prognostic risk factor for outcomes after elective surgery, whereas frailty could be. A simple and easy-to-get marker for frailty, such as handgrip strength (HGS), may support the surgeon in decision for an adequate healthcare plan.
Aims
The aims of this study were to: (1) determine the prevalence of frailty in an abdominal surgery setting independent of age; (2) evaluate the predictive validity of HGS for the length of hospital stay (LOS).
Methods
This is a retrospective study conducted in subjects who underwent abdominal surgical procedures. Only subjects with complete cognitive, functional, nutritional assessments and available measurement of HGS at admission were included. A final cohort of 108 patients were enrolled in the study.
Results
Subjects had a mean age of 67.8 ± 15.8 years (age range 19–93 years old) and were mostly men. According to Fried’s criteria, 17 (15.7%, 4F/13 M) were fit, 58 (23.7%; 24F/34 M) were pre-frail and 33 (30.6%; 20F/13 M) were frail. As expected, HGS significantly differed between groups having frail lower values as compared with pre-frail and fit persons (fit: 32.99 ± 10.34 kg; pre-frail: 27.49 ± 10.35 kg; frail: 15.96 ± 9.52 kg,
p
|
| doi_str_mv | 10.1007/s40520-022-02121-z |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9076715</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2660201041</sourcerecordid><originalsourceid>FETCH-LOGICAL-c474t-ccbf604372e7bca1edbcd3cefeb25adde09f7b94f4deb210458cc621242a69863</originalsourceid><addsrcrecordid>eNp9Uctu3SAURFWjJr3tD3RRIXXTjRPAGNtZRKqiNokUqZt2jTAc-xL5ggO40s3XF9dpXotIIM5jZoAzCH2i5JgSUp9ETipGCsJY3pTR4u4NOqJ1LjUlbd8-iQ_R-xhvCOE0J-_QYVmVTUsbcYTipXJmCHbCMQVwQ9riKYCxOkU8rrnv8dbHySY1ZpDaY-uwyqszfmfdUpzDYPUSQErWDac4bQEHP8LC7YOyY9rjDvbeGawG-IAOejVG-Hh_btDvH99_nV8W1z8vrs6_XRea1zwVWne9ILysGdSdVhRMp02poYeOVcoYIG1fdy3vuckVSnjVaC3yIDhTom1EuUFnq-40dzswGlwKapRTsDsV9tIrK593nN3Kwf-RLalFTass8PVeIPjbGWKSOxs1jKNy4OcomeANEUxQmqFfXkBv_BzydBaUIIzQZfgbxFaUDj7GAP3DYyiRi6dy9VRmT-U_T-VdJn1--o0Hyn8TM6BcATG33ADh8e5XZP8CdvuwXw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2660201041</pqid></control><display><type>article</type><title>Handgrip strength predicts length of hospital stay in an abdominal surgical setting: the role of frailty beyond age</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Marano, Luigi ; Carbone, Ludovico ; Poto, Gianmario Edoardo ; Gambelli, Margherita ; Nguefack Noudem, Leonelle Lore ; Grassi, Giulia ; Manasci, Fabiana ; Curreri, Giulia ; Giuliani, Alessandra ; Piagnerelli, Riccardo ; Savelli, Vinno ; Marrelli, Daniele ; Roviello, Franco ; Boccardi, Virginia</creator><creatorcontrib>Marano, Luigi ; Carbone, Ludovico ; Poto, Gianmario Edoardo ; Gambelli, Margherita ; Nguefack Noudem, Leonelle Lore ; Grassi, Giulia ; Manasci, Fabiana ; Curreri, Giulia ; Giuliani, Alessandra ; Piagnerelli, Riccardo ; Savelli, Vinno ; Marrelli, Daniele ; Roviello, Franco ; Boccardi, Virginia</creatorcontrib><description>Background
Chronological age per se cannot be considered a prognostic risk factor for outcomes after elective surgery, whereas frailty could be. A simple and easy-to-get marker for frailty, such as handgrip strength (HGS), may support the surgeon in decision for an adequate healthcare plan.
Aims
The aims of this study were to: (1) determine the prevalence of frailty in an abdominal surgery setting independent of age; (2) evaluate the predictive validity of HGS for the length of hospital stay (LOS).
Methods
This is a retrospective study conducted in subjects who underwent abdominal surgical procedures. Only subjects with complete cognitive, functional, nutritional assessments and available measurement of HGS at admission were included. A final cohort of 108 patients were enrolled in the study.
Results
Subjects had a mean age of 67.8 ± 15.8 years (age range 19–93 years old) and were mostly men. According to Fried’s criteria, 17 (15.7%, 4F/13 M) were fit, 58 (23.7%; 24F/34 M) were pre-frail and 33 (30.6%; 20F/13 M) were frail. As expected, HGS significantly differed between groups having frail lower values as compared with pre-frail and fit persons (fit: 32.99 ± 10.34 kg; pre-frail: 27.49 ± 10.35 kg; frail: 15.96 ± 9.52 kg,
p
< 0.0001). A final regression analysis showed that HGS was significantly and inversely associated with LOS (
p
= 0.020) independent of multiple covariates, including age.
Discussion
Most of the population undergoing abdominal surgery is pre-frail or frail. The measurement of handgrip strength is simple and inexpensive, and provides prognostic information for surgical outcomes. Muscle strength, as measured by handgrip dynamometry, is a strong predictor of LOS in a surgical setting.</description><identifier>ISSN: 1720-8319</identifier><identifier>ISSN: 1594-0667</identifier><identifier>EISSN: 1720-8319</identifier><identifier>DOI: 10.1007/s40520-022-02121-z</identifier><identifier>PMID: 35389186</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Abdomen ; Abdominal surgery ; Age ; Aged ; Aged, 80 and over ; Female ; Frail Elderly ; Frailty ; Frailty - diagnosis ; Geriatrics/Gerontology ; Hand Strength ; Humans ; Length of Stay ; Male ; Medicine ; Medicine & Public Health ; Original ; Original Article ; Retrospective Studies ; Surgical outcomes</subject><ispartof>Aging clinical and experimental research, 2022-04, Vol.34 (4), p.811-817</ispartof><rights>The Author(s) 2022. corrected publication 2022</rights><rights>2022. The Author(s).</rights><rights>The Author(s) 2022. corrected publication 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2022, corrected publication 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-ccbf604372e7bca1edbcd3cefeb25adde09f7b94f4deb210458cc621242a69863</citedby><cites>FETCH-LOGICAL-c474t-ccbf604372e7bca1edbcd3cefeb25adde09f7b94f4deb210458cc621242a69863</cites><orcidid>0000-0003-2134-1122</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s40520-022-02121-z$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s40520-022-02121-z$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35389186$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Marano, Luigi</creatorcontrib><creatorcontrib>Carbone, Ludovico</creatorcontrib><creatorcontrib>Poto, Gianmario Edoardo</creatorcontrib><creatorcontrib>Gambelli, Margherita</creatorcontrib><creatorcontrib>Nguefack Noudem, Leonelle Lore</creatorcontrib><creatorcontrib>Grassi, Giulia</creatorcontrib><creatorcontrib>Manasci, Fabiana</creatorcontrib><creatorcontrib>Curreri, Giulia</creatorcontrib><creatorcontrib>Giuliani, Alessandra</creatorcontrib><creatorcontrib>Piagnerelli, Riccardo</creatorcontrib><creatorcontrib>Savelli, Vinno</creatorcontrib><creatorcontrib>Marrelli, Daniele</creatorcontrib><creatorcontrib>Roviello, Franco</creatorcontrib><creatorcontrib>Boccardi, Virginia</creatorcontrib><title>Handgrip strength predicts length of hospital stay in an abdominal surgical setting: the role of frailty beyond age</title><title>Aging clinical and experimental research</title><addtitle>Aging Clin Exp Res</addtitle><addtitle>Aging Clin Exp Res</addtitle><description>Background
Chronological age per se cannot be considered a prognostic risk factor for outcomes after elective surgery, whereas frailty could be. A simple and easy-to-get marker for frailty, such as handgrip strength (HGS), may support the surgeon in decision for an adequate healthcare plan.
Aims
The aims of this study were to: (1) determine the prevalence of frailty in an abdominal surgery setting independent of age; (2) evaluate the predictive validity of HGS for the length of hospital stay (LOS).
Methods
This is a retrospective study conducted in subjects who underwent abdominal surgical procedures. Only subjects with complete cognitive, functional, nutritional assessments and available measurement of HGS at admission were included. A final cohort of 108 patients were enrolled in the study.
Results
Subjects had a mean age of 67.8 ± 15.8 years (age range 19–93 years old) and were mostly men. According to Fried’s criteria, 17 (15.7%, 4F/13 M) were fit, 58 (23.7%; 24F/34 M) were pre-frail and 33 (30.6%; 20F/13 M) were frail. As expected, HGS significantly differed between groups having frail lower values as compared with pre-frail and fit persons (fit: 32.99 ± 10.34 kg; pre-frail: 27.49 ± 10.35 kg; frail: 15.96 ± 9.52 kg,
p
< 0.0001). A final regression analysis showed that HGS was significantly and inversely associated with LOS (
p
= 0.020) independent of multiple covariates, including age.
Discussion
Most of the population undergoing abdominal surgery is pre-frail or frail. The measurement of handgrip strength is simple and inexpensive, and provides prognostic information for surgical outcomes. Muscle strength, as measured by handgrip dynamometry, is a strong predictor of LOS in a surgical setting.</description><subject>Abdomen</subject><subject>Abdominal surgery</subject><subject>Age</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Female</subject><subject>Frail Elderly</subject><subject>Frailty</subject><subject>Frailty - diagnosis</subject><subject>Geriatrics/Gerontology</subject><subject>Hand Strength</subject><subject>Humans</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original</subject><subject>Original Article</subject><subject>Retrospective Studies</subject><subject>Surgical outcomes</subject><issn>1720-8319</issn><issn>1594-0667</issn><issn>1720-8319</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9Uctu3SAURFWjJr3tD3RRIXXTjRPAGNtZRKqiNokUqZt2jTAc-xL5ggO40s3XF9dpXotIIM5jZoAzCH2i5JgSUp9ETipGCsJY3pTR4u4NOqJ1LjUlbd8-iQ_R-xhvCOE0J-_QYVmVTUsbcYTipXJmCHbCMQVwQ9riKYCxOkU8rrnv8dbHySY1ZpDaY-uwyqszfmfdUpzDYPUSQErWDac4bQEHP8LC7YOyY9rjDvbeGawG-IAOejVG-Hh_btDvH99_nV8W1z8vrs6_XRea1zwVWne9ILysGdSdVhRMp02poYeOVcoYIG1fdy3vuckVSnjVaC3yIDhTom1EuUFnq-40dzswGlwKapRTsDsV9tIrK593nN3Kwf-RLalFTass8PVeIPjbGWKSOxs1jKNy4OcomeANEUxQmqFfXkBv_BzydBaUIIzQZfgbxFaUDj7GAP3DYyiRi6dy9VRmT-U_T-VdJn1--o0Hyn8TM6BcATG33ADh8e5XZP8CdvuwXw</recordid><startdate>20220401</startdate><enddate>20220401</enddate><creator>Marano, Luigi</creator><creator>Carbone, Ludovico</creator><creator>Poto, Gianmario Edoardo</creator><creator>Gambelli, Margherita</creator><creator>Nguefack Noudem, Leonelle Lore</creator><creator>Grassi, Giulia</creator><creator>Manasci, Fabiana</creator><creator>Curreri, Giulia</creator><creator>Giuliani, Alessandra</creator><creator>Piagnerelli, Riccardo</creator><creator>Savelli, Vinno</creator><creator>Marrelli, Daniele</creator><creator>Roviello, Franco</creator><creator>Boccardi, Virginia</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2134-1122</orcidid></search><sort><creationdate>20220401</creationdate><title>Handgrip strength predicts length of hospital stay in an abdominal surgical setting: the role of frailty beyond age</title><author>Marano, Luigi ; Carbone, Ludovico ; Poto, Gianmario Edoardo ; Gambelli, Margherita ; Nguefack Noudem, Leonelle Lore ; Grassi, Giulia ; Manasci, Fabiana ; Curreri, Giulia ; Giuliani, Alessandra ; Piagnerelli, Riccardo ; Savelli, Vinno ; Marrelli, Daniele ; Roviello, Franco ; Boccardi, Virginia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-ccbf604372e7bca1edbcd3cefeb25adde09f7b94f4deb210458cc621242a69863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Abdomen</topic><topic>Abdominal surgery</topic><topic>Age</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Female</topic><topic>Frail Elderly</topic><topic>Frailty</topic><topic>Frailty - diagnosis</topic><topic>Geriatrics/Gerontology</topic><topic>Hand Strength</topic><topic>Humans</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Original</topic><topic>Original Article</topic><topic>Retrospective Studies</topic><topic>Surgical outcomes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Marano, Luigi</creatorcontrib><creatorcontrib>Carbone, Ludovico</creatorcontrib><creatorcontrib>Poto, Gianmario Edoardo</creatorcontrib><creatorcontrib>Gambelli, Margherita</creatorcontrib><creatorcontrib>Nguefack Noudem, Leonelle Lore</creatorcontrib><creatorcontrib>Grassi, Giulia</creatorcontrib><creatorcontrib>Manasci, Fabiana</creatorcontrib><creatorcontrib>Curreri, Giulia</creatorcontrib><creatorcontrib>Giuliani, Alessandra</creatorcontrib><creatorcontrib>Piagnerelli, Riccardo</creatorcontrib><creatorcontrib>Savelli, Vinno</creatorcontrib><creatorcontrib>Marrelli, Daniele</creatorcontrib><creatorcontrib>Roviello, Franco</creatorcontrib><creatorcontrib>Boccardi, Virginia</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Aging clinical and experimental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Marano, Luigi</au><au>Carbone, Ludovico</au><au>Poto, Gianmario Edoardo</au><au>Gambelli, Margherita</au><au>Nguefack Noudem, Leonelle Lore</au><au>Grassi, Giulia</au><au>Manasci, Fabiana</au><au>Curreri, Giulia</au><au>Giuliani, Alessandra</au><au>Piagnerelli, Riccardo</au><au>Savelli, Vinno</au><au>Marrelli, Daniele</au><au>Roviello, Franco</au><au>Boccardi, Virginia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Handgrip strength predicts length of hospital stay in an abdominal surgical setting: the role of frailty beyond age</atitle><jtitle>Aging clinical and experimental research</jtitle><stitle>Aging Clin Exp Res</stitle><addtitle>Aging Clin Exp Res</addtitle><date>2022-04-01</date><risdate>2022</risdate><volume>34</volume><issue>4</issue><spage>811</spage><epage>817</epage><pages>811-817</pages><issn>1720-8319</issn><issn>1594-0667</issn><eissn>1720-8319</eissn><abstract>Background
Chronological age per se cannot be considered a prognostic risk factor for outcomes after elective surgery, whereas frailty could be. A simple and easy-to-get marker for frailty, such as handgrip strength (HGS), may support the surgeon in decision for an adequate healthcare plan.
Aims
The aims of this study were to: (1) determine the prevalence of frailty in an abdominal surgery setting independent of age; (2) evaluate the predictive validity of HGS for the length of hospital stay (LOS).
Methods
This is a retrospective study conducted in subjects who underwent abdominal surgical procedures. Only subjects with complete cognitive, functional, nutritional assessments and available measurement of HGS at admission were included. A final cohort of 108 patients were enrolled in the study.
Results
Subjects had a mean age of 67.8 ± 15.8 years (age range 19–93 years old) and were mostly men. According to Fried’s criteria, 17 (15.7%, 4F/13 M) were fit, 58 (23.7%; 24F/34 M) were pre-frail and 33 (30.6%; 20F/13 M) were frail. As expected, HGS significantly differed between groups having frail lower values as compared with pre-frail and fit persons (fit: 32.99 ± 10.34 kg; pre-frail: 27.49 ± 10.35 kg; frail: 15.96 ± 9.52 kg,
p
< 0.0001). A final regression analysis showed that HGS was significantly and inversely associated with LOS (
p
= 0.020) independent of multiple covariates, including age.
Discussion
Most of the population undergoing abdominal surgery is pre-frail or frail. The measurement of handgrip strength is simple and inexpensive, and provides prognostic information for surgical outcomes. Muscle strength, as measured by handgrip dynamometry, is a strong predictor of LOS in a surgical setting.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>35389186</pmid><doi>10.1007/s40520-022-02121-z</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-2134-1122</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1720-8319 |
| ispartof | Aging clinical and experimental research, 2022-04, Vol.34 (4), p.811-817 |
| issn | 1720-8319 1594-0667 1720-8319 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9076715 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Abdomen Abdominal surgery Age Aged Aged, 80 and over Female Frail Elderly Frailty Frailty - diagnosis Geriatrics/Gerontology Hand Strength Humans Length of Stay Male Medicine Medicine & Public Health Original Original Article Retrospective Studies Surgical outcomes |
| title | Handgrip strength predicts length of hospital stay in an abdominal surgical setting: the role of frailty beyond age |
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