GSK3β Exacerbates Myocardial Ischemia/Reperfusion Injury by Inhibiting Myc

Myocardial ischemia/reperfusion (MI/R) injury is a life-threatening disease with high morbidity and mortality. Herein, the present study is conducted to explore the regulatory mechanism of GSK3β in MI/R injury regarding cardiomyocyte apoptosis and oxidative stress. The MI/R injury mouse model and hy...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2022, Vol.2022, p.2588891-23
Hauptverfasser:	Wen, Cong, Lan, Meide, Tan, Xin, Wang, Xiaobo, Zheng, Zaiyong, Lv, Mingming, Zhao, Xuemei, Luo, Hao, Liu, Yanxu, Wei, Ping, Yue, Rongchuan, Hu, Houxiang, Guo, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses Animals Apoptosis Binding sites Bioengineering Bioinformatics Cardiomyocytes Cell cycle Coronary vessels Disease Models, Animal Gene expression Glycogen Synthase Kinase 3 beta - metabolism Heart attacks Ischemia Kinases Laboratory animals Mice Myocardial Reperfusion Injury - metabolism Myocytes, Cardiac - metabolism Oxidative Stress Pulmonary arteries Sutures Veins & arteries
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