Mito-FUNCAT-FACS reveals cellular heterogeneity in mitochondrial translation

Mitochondria possess their own genome that encodes components of oxidative phosphorylation (OXPHOS) complexes, and mitochondrial ribosomes within the organelle translate the mRNAs expressed from the mitochondrial genome. Given the differential OXPHOS activity observed in diverse cell types, cell gro...

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Veröffentlicht in:	RNA (Cambridge) 2022-06, Vol.28 (6), p.895-904
Hauptverfasser:	Kimura, Yusuke, Saito, Hironori, Osaki, Tatsuya, Ikegami, Yasuhiro, Wakigawa, Taisei, Ikeuchi, Yoshiho, Iwasaki, Shintaro
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Amino Acids - chemistry Flow Cytometry Fluorophores Genomes Growth conditions Marking and tracking techniques Methionine Method Mitochondria Mitochondria - genetics Mitochondria - metabolism Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism Oxidative phosphorylation Phosphorylation Protein Biosynthesis Protein synthesis Proteins Ribosomes Translation
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