Efficacy and Safety of Difelikefalin in Japanese Patients With Moderate to Severe Pruritus Receiving Hemodialysis: A Randomized Clinical Trial

Patients with pruritus receiving hemodialysis frequently experience oppressive physical and psychiatric symptoms that directly affect their quality of life and increase mortality. However, treatment options are limited. To determine the clinically recommended dose of difelikefalin, a κ-opioid recept...

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Veröffentlicht in:JAMA network open 2022-05, Vol.5 (5), p.e2210339-e2210339
Hauptverfasser: Narita, Ichiei, Tsubakihara, Yoshiharu, Uchiyama, Takuma, Okamura, Shota, Oya, Nobuyo, Takahashi, Naoki, Gejyo, Fumitake
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Sprache:eng
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