12p gain is predominantly observed in non-germinomatous germ cell tumors and identifies an unfavorable subgroup of central nervous system germ cell tumors

Abstract Background Central nervous system (CNS) germ cell tumors (GCTs) are neoplasms predominantly arising in pediatric and young adult populations. While germinomas generally respond to chemotherapy and radiation, non-germinomatous GCTs (NGGCTs) require more intensive treatment. This study aimed...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2022-05, Vol.24 (5), p.834-846
Hauptverfasser:	Satomi, Kaishi, Takami, Hirokazu, Fukushima, Shintaro, Yamashita, Satoshi, Matsushita, Yuko, Nakazato, Yoichi, Suzuki, Tomonari, Tanaka, Shota, Mukasa, Akitake, Saito, Nobuhito, Kanamori, Masayuki, Kumabe, Toshihiro, Tominaga, Teiji, Kobayashi, Keiichi, Nagane, Motoo, Iuchi, Toshihiko, Yoshimoto, Koji, Tamura, Kaoru, Maehara, Taketoshi, Sakai, Keiichi, Sugiyama, Kazuhiko, Yokogami, Kiyotaka, Takeshima, Hideo, Nonaka, Masahiro, Asai, Akio, Ushijima, Toshikazu, Matsutani, Masao, Nishikawa, Ryo, Ichimura, Koichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Neoplasms - genetics Brain Neoplasms - therapy Central Nervous System Neoplasms - genetics Central Nervous System Neoplasms - pathology Child Germinoma Humans In Situ Hybridization, Fluorescence Male Neoplasms, Germ Cell and Embryonal - genetics Neoplasms, Germ Cell and Embryonal - therapy Pediatric Neuro-Oncology Pineal Gland - pathology Testicular Neoplasms
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