TRIM44 promotes BRCA1 functions in HR repair to induce Cisplatin Chemoresistance in Lung Adenocarcinoma by Deubiquitinating FLNA

Tripartite motif-containing 44 (TRIM44) has recently been implicated in various pathological processes in numerous cancers, including lung adenocarcinoma (LUAD); however, its functional roles in chemoresistance are poorly understood. Herein, TRIM44 knockdown sensitized LUAD cells to cisplatin and en...

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Veröffentlicht in:International journal of biological sciences 2022-01, Vol.18 (7), p.2962-2979
Hauptverfasser: Zhang, Shuai, Cao, Mengru, Yan, Shi, Liu, Yuechao, Fan, Weina, Cui, Yimeng, Tian, Fanglin, Gu, Ruixue, Cui, Yaowen, Zhan, Yuning, Sun, Yuanyuan, Xing, Ying, Cai, Li, Song, Yang
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Sprache:eng
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