Mechanisms tailoring the expression of heat shock proteins to proteostasis challenges

All cells possess an internal stress response to cope with environmental and pathophysiological challenges. Upon stress, cells reprogram their molecular functions to activate a survival mechanism known as the heat shock response, which mediates the rapid induction of molecular chaperones such as the...

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Veröffentlicht in:	The Journal of biological chemistry 2022-05, Vol.298 (5), p.101796-101796, Article 101796
Hauptverfasser:	Alagar Boopathy, Lokha R., Jacob-Tomas, Suleima, Alecki, Célia, Vera, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	acclimation gene expression heat shock factor 1 heat shock proteins heat shock response Heat-Shock Proteins - metabolism Heat-Shock Response - physiology JBC Reviews Molecular Chaperones - genetics Molecular Chaperones - metabolism mRNA decay Proteostasis Signal Transduction stress-regulated translation
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